Molecular Virology - Course Information

Rutgers GSBS MICR 5231
Spring 2016 (April 26 - June 2)

 

Instructors: Hua Zhu, Ph.D. ( zhuhu@njms.rutgers.edu, 973-972-6488)
Ian Whitehead, Ph.D. ( whiteip@njms.rutgers.edu, 973-972-5215)
David Lukac, Ph.D. ( lukacdm@njms.rutgers.edu, 973-972-4868)

 

Lecture time: 5:30-8:30 PM, Monday, Tuesday and Thursday

Lecture room: ICPH Auditorium (225 Warren Street)

Office hours: By appointment

Credits: 3

COURSE DESCRIPTION

This course includes lectures and student presentations based on recent research publications.? The goal of this course is to introduce students to the basic principles of virus-host cell interactions and the molecular basis of viral pathogenesis. All important human viruses will be discussed, including papilloma, herpes, smallpox, polio, measles, West Nile, Ebola, HIV, influenza, SARS and hepatitis viruses. Lectures cover viral structures; viral strategies of invasion, transcription, replication, and dissemination; viral offense and host defense; prevention and control of viral diseases; and approaches for studying viruses.

COURSE WEB SITE

All lectures are posted on Moodle:

http://moodle.rutgers.edu/course/view.php?id=1698

COURSE RECORDING

We will try to record the lectures.

EXAMINATIONS AND GRADING

Students are responsible for and will be tested on all lecture contents and reading materials. Two exams, a midterm, and a final are scheduled. Each exam will stress the preceding block of lectures and readings. Students are required to complete all multiple-choice questions independently (closed book) in class. Make-up exams will only be given if the student has a valid excuse.

Grades:
Midterm Exam: 40%
Final Exam: 50%
Readings: 10%

Grading scale:
90% and above: A
85% to 89.9%: B+
80% to 84.9%: B
75% to 79.9%: C+
70% to 74.9%: C
60% to 69.9%: D
<60%: F

READINGS

(See distributed instruction)

SCHEDULE*

Course Coordinator: Hua Zhu, Ph.D.

Class #

Date

Day

Topic

Lecturer

1

4/26

Tue

Introduction to Virology

Whitehead

2

5/3

Tue

Approaches for Studying Animal Viruses

Zhu

3

5/5

Thu

Virus-Host Interaction, Vaccines and Antivirals

Zhu

4

5/9**

Thu

Readings

Zhu

5

5/10

Tue

Small DNA viruses (Parvo, Papova and Adenoviruses)

Lukac

6

5/12

Thu

Large DNA viruses (Herpes and Pox Viruses)

Zhu

7

5/16

Mon

Positive Strand RNA Viruses

Zhu

8

5/17

Tue

Non-segmented Negative Strand RNA Viruses

Zhu

9

5/19

Thu

Midterm Exam

Zhu

10

5/23

Mon

Segmented RNA Viruses/Influenza Viruses

Lukac

11

5/24

Tue

Retroviruses, HIV and AIDS

Whitehead

12

5/26

Thu

Hepatitis Viruses & Slow and Unconventional Virus

Whitehead

13

5/31

Tue

Transformation and Oncogenesis

Emerging and Reemerging viruses

Lukac

Zhu

14

6/2

Thu

Final Exam

Zhu

* Please note that the above information is subject to change

** Take home - no meeting