James P. O'Connor, Ph.D.

Publications

(Listed in chronological order with most recent last)

1. O'Connor, J. Patrick and Craig L. Peebles. 1991. In vivo tRNA Processing in Saccharomyces cerevisiae. Molecular and Cellular Biology 11:425-439.

2. O'Connor, J. Patrick and Craig L. Peebles. 1992. PTA1, an essential gene of Saccharomyces cerevisiae affecting pre-tRNA processing. Molecular and Cellular Biology 12:3843-3856.

3. Kaplan, F.S., J. Murray, J.E. Sylvester, I.L. Gonzalez, J.P. O'Connor , J.L. Doering, M. Muenke, B.S. Emanuel, and M.A. Zasloff. 1993. The topographic organization of repetitive DNA in the human nucleolus. Genomics 15:123-132.

4. Kaplan, Frederick S., and J. Patrick O'Connor . 1995. Topographic changes in a heterochromatic chromosome block in humans (15P) during formation of the nucleolus. Chromosome Research 3:309-314.

5. Zhang, Yan, J. Patrick O'Connor , Sudha Srinivasan, Amita Dutra, Robert L. Nussbaum, and Gideon Dreyfuss. 1995. The Fragile X Mental Retardation Syndrome Protein Interacts with Novel Homologs FXR1 and FXR2. EMBO J. 14:5358-5366.

6. Lutz, Carol S., Kanneganti G. K. Murthy, Nancy Schek, J. Patrick O'Connor , James Manley, and James C. Alwine. 1996. Interaction between the U1 snRNP-A protein and the 160kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes and Development 10:325-337.

7. Traglia, Helen M., J. Patrick O'Connor , Kuei-Shu Tung, Susan Dallabrida, Wu-Cheng Shen, and Anita K. Hopper. 1996. Nucleus-associated pools of Rna1p, the Saccharomyces cerevisiae Ran/TC4 GTPase activating protein involved in nucleus/cytosol transit. Proceedings National Academy of Sciences USA 93:7667-7672.

8. Portman, Douglas, J. Patrick O'Connor , and Gideon Dreyfuss. 1997. YRA1: an Essential Saccharomyces cerevisiae Gene that Encodes a Nuclear Protein with RNA Annealing Activity. RNA 3:527-537.

9. O'Connor, J. Patrick , Carol S. Lutz, Gideon Dreyfuss, and James C. Alwine. 1997. Identification of a Novel Protein Complex that Contains the U1 snRNP-A Protein and is Necessary for Efficient pre-mRNA Polyadenylation. RNA 3:1444-1455.

10. O'Connor, J. Patrick. 1998. Animal models of heterotopic ossification. Clinical Orthopaedics and Related Research.346:71-80.

11. Lutz, Carol S., Charles L. Cooke, J. Patrick O'Connor , Ryuji Kobayashi, and James C. Alwine. 1998. The snRNP-Free U1A (SF-A) Complex: Identification of the Largest Subunit as PSF, the Polypyrimidine Tract Binding Protein Associated Splicing Factor. RNA 4:1493-1499.

12. Zhao, Jing, Marco Kessler, J. Patrick O'Connor , and Claire Moore. 1999. Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursors. Molecular and Cellular Biology 19:7733-7740.

13. Mukherjee, D., M. Gao, J. Patrick O'Connor , R. Raijmakers, G. Pruijn, C.S. Lutz, and J. Wilusz. 2002. Messenger RNA decay by the human exosome is regulated through AU-rich elements. EMBO J. 21:165-174.

14. Simon, Ann Marie, Michaele Beth Manigrasso, and J. Patrick O'Connor . 2002. COX-2 function is essential for bone fracture healing. Journal of Bone and Mineral Research 17: 963-976.

15. Tyndall, W.A., H.A. Beam, C. Zarro, J. Patrick O'Connor , and S.S. Lin. 2003. Decreased platelet derived growth factor expression during diabetic fracture healing. Clinical Orthopaedics and Related Research 408:319-330.

16. Balaburski, G. and J. Patrick O'Connor . 2003. Determination of gene expression variation during fracture healing. Acta Orthopaedica Scandinavica 74:16-21.

17. Chen, F, M Wang, JP O'Connor , M He, T Tripathi, and LE Harrison. 2003. Phosphorylation of PPARg via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kB. J. Cell. Biochem. 90:732-744.

18. Manigrasso, M.B. and J. Patrick O'Connor . In press. Charcterization of a closed femur fracture model in mice. Journal of Orthopaedic Trauma.

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