K. Singh , and M. J. Modak (1998). A unified DNA- and dNTP-binding mode for DNA polymerases. Trends Biochem. Sci 23 , 277-281. |
| N. Kaushik, K. Singh, I. Alluru and M. J. Modak (1999). Tyrosine 222, a member of YXDD motif of MuLV RT, is catalytically essential and is a major component of fidelity center. Biochemistry 38 , 2617-2627. |
| J. Jin, N. Kaushik, K. Singh and M. J. Modak (1999). Analysis of the role of glutamine 190 in the catalytic mechanism of murine leukemia virus reverse transcriptase. J. Biol. Chem . 274 , 20861-2086. |
| R. Gangurde, N. Kaushik, K. Singh and M. J. Modak, (2000). A carboxylate triad is essential for polymerase activity of Escherichia coli DNA polymerase I (Klenow Fragment): Presence of two functional triads at the catalytic center. J. Biol. Chem . 275: 19685-19692. |
| S. Tuske*, K. Singh*, N. Kaushik and M. J. Modak (2000). The J-Helix of E. coli DNA Polymerase I (Klenow fragment) Regulates Polymerase and 3'- 5' Exonuclease Functions. J. Biol. Chem. 275 , 23759-23768. (*equal contribution). |
| K. Singh , N. Kaushik, J. Jin, M. Madhusudanan, and M. J. Modak, (2000). Role of Q190 of MuLV RT in ddNTP resistance and fidelity of DNA synthesis: A molecular model of interactions with substrates. Prot. Eng. 13 , 635-643. |
| Cindy, J. Arrigo, K. Singh and M. J. Modak (2002). DNA polymerase I from Mycobacterium tuberculosis : Functional role of a conserved aspartate in the hinge joining M and N helices. J. Biol. Chem. 277 :1653-1661. |
| Gangurde, R.; Modak, M. J (2002). Participation of Active-Site Carboxylates of Escherichia coli DNA Polymerase I (Klenow Fragment) in the Formation of a Prepolymerase Ternary Complex . Biochemistry 41 ; 14552-14559. |
| Q. Shi*, K. Singh*, A. Srivastava, N. Kaushik and M. J. Modak (2002). Lys152 of MuLV reverse transcriptase is required for the integrity of the active site. Biochemistry 41 : 14831-14842 (*equal contribution). |
| Srivastava, K. Singh and M. J. Modak (2003) Phe 771 of E.coli DNA polymerase I (Klenow Fragment) is the Major Site for the Interaction with Template Overhang and the Stabilization of Pre-polymerase Ternary Complex. Biochemistry 42 : 3645 ? 3654. K. Singh and M. J. Modak (2003) Presence Of 18 ? Long Hydrogen Bond Track in the Active Site of E.coli DNA Polymerase I (Klenow Fragment): Its Requirement in the Stabilization Of Enzyme -Template - Primer Complex. J. Biol. Chem . 278 : 11289 - 11302. |
|