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Department of Radiology

Roger W. Howell, Ph.D.


Professor
Chief, Division of Radiation Research

Department of Radiology
rhowell@njms.rutgers.edu
 
Research

Cancer Research Center (CANCT)
195 South Orange Avenue Room F1208

Phone: (973) 972-5067
Fax: (973) 972-6474

Biography

Overview

Dr. Howell is a Professor of Radiology at Rutgers New Jersey Medical School. He
received his bachelor’s degree in physics in 1982 and a doctorate in 1987 from the
University of Massachusetts (Amherst). He is Chief of the Division of Radiation
Research and Chair of the Rutgers Radiation Safety Committee. Dr. Howell has authored
over 100 scientific publications on radiation dosimetry and radiobiology of internal
radionuclides, including two books and two patents. Professor Howell serves on the
Society of Nuclear Medicine’s Medical Internal Radiation Dose Committee. He has served
on committees for NCRP Report 167 Potential impact of individual genetic
susceptibility and previous radiation exposure on radiation risk for astronauts, ICRU
Report 67 Absorbed dose specification in nuclear medicine, ICRU Report 86
Quantification and reporting of low-dose and other heterogeneous exposures, and he
serves on the International Commission on Radiation Units and Measurements. He is the
recipient of the 2004 Loevinger-Berman Award from the Society of Nuclear Medicine and
New Jersey Medical School’s 2009 Basic Science Faculty of the Year Award.

 

Education

Ph.D., 1987, University of Massachusetts, Physics

 

Curriculum Vitae

View CV

 

 

Publications

Relevant Publications:

J. M. Akudugu and R. W. Howell, A method to predict response of cell populations to cocktails of chemotherapeutics and radiopharmaceuticals: Validation with daunomycin, doxorubicin, and the alpha particle emitter 210Po. Nucl Med Biol 39, 954-961 (2012).
J. M. Akudugu and R. W. Howell, Flow cytometry-assisted Monte Carlo simulation predicts clonogenic survival of cell populations with lognormal distributions of radiopharmaceuticals and anticancer drugs. Int J Radiat Biol 88, 286-293 (2012).
R. F. Hobbs, R. W. Howell, H. Song, S. Baechler and G. Sgouros, Redefining Relative Biological Effectiveness in the Context of the EQDX Formalism: Implications for Alpha- Particle Emitter Therapy. Radiat Res 181, 90-98 (2014).
B. Vaziri, H. Wu, A. P. Dhawan, P. Du, R. W. Howell, S. M. Committee and S. M. Committee, MIRD Pamphlet No. 25: MIRDcell V2.0 Software Tool for Dosimetric Analysis of Biologic Response of Multicellular Populations. J Nucl Med 55, 1557-1564 (2014).
J. B. Pasternack, J. D. Domogauer, A. Khullar, J. M. Akudugu and R. W. Howell, The advantage of antibody cocktails for targeted alpha therapy depends on specific activity. J Nucl Med 55, 2012-2019 (2014).
Buonanno M, De Toledo SM, Howell RW, Azzam EI. Low-dose energetic protons induce adaptive and bystander effects that protect human cells against DNA damage caused by a subsequent exposure to energetic iron ions. Journal of radiation research (Tokyo). May 2015;56(3):502-508.
Roche M, Neti PV, Kemp FW, Azzam EI, Ferraris RP, Howell RW. High Levels of Dietary Supplement Vitamins A, C and E are Absorbed in the Small Intestine and Protect Nutrient Transport Against Chronic Gamma Irradiation. Radiat Res. Oct 20 2015;184(5):470-481.
Howell RW. Physical Considerations for Understanding Responses of Biological Systems to Low Doses of Ionizing Radiation: Nucleosome Clutches Constitute a Heterogeneous Distribution of Target Volumes. Health Phys. Mar 2016;110(3):283-286.
Kemp FW, Portugal F, Akudugu JM, Neti PV, Ferraris RP, Howell RW. Vitamins A, C, and E May Reduce Intestinal 210Po Levels after Ingestion. Health Phys. Jul 2016;111(1):52-57.

 

 

 

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