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Department of Pharmacology, Physiology & Neuroscience

Teresa Wood, Ph.D.

Rena Warshow Endowed Chair in Multiple Sclerosis
Dept. Pharmacology, Physiology & Neuroscience

Department of Pharmacology, Physiology & Neuroscience

Cancer Research Center (CANCT)
195 South Orange Avenue Room H1200

Phone: (973) 972-6529



Lab Members

Teresa (Terri) L. Wood, PhD

Research: The Wood laboratory is focused on determining how growth factors and signaling pathways
interact to promote growth, survival and differentiation of breast epithelial and neural progenitor cells. We
conduct both in vitro and in vivo studies and make use of mouse models carrying genetic alterations in
genes of interest, particularly in the insulin-like growth factor family of ligands and receptors and in the
mTOR signaling pathway. These studies are designed to reveal normal functions of these signaling systems
in growth and development as well as abnormal functions in cancer and neurological disorders.

Quan Shang, Research Associate

Alison Obr, Postdoctoral Researcher

Luipa Khandker, Grad Student

Angelina Evangelou, Grad Student

Marisa Jeffries, Grad Student

Joseph Bulatowicz, Grad Student



Ph.D., 1987, University of California, Los Angeles


Curriculum Vitae

View CV




Relevant Publications:

McLane, L.E., Bourne, J.N., Evangelou, A.V., Khandker, L., Macklin, W.B. and Wood, T.L. (2017) Loss of tuberous sclerosis complex 1 in adult oligodendrocyte progenitor cells enhances axon remyelination and increases myelin thickness after a focal demyelination. J. Neuroscience 37:7534-7546.
Flannery, C.A., Rowzee, A.M., Choe, G., Saleh, F., Taylor, H.S. and Wood, T.L. (2016) Development of a quantitative PCR assay for detection of human insulin-like growth factor receptor and insulin receptor isoforms. Endocrinology 157:1702-8.
Rota, L.M. and Wood, T.L. (2015) Crosstalk of the insulin-like growth factor receptor with the Wnt signaling pathway in breast cancer. (invited mini-review) Frontiers in Endocrinology, section Cancer Endocrinology Jun 9;6:92. doi: 10.3389/fendo.2015.00092. eCollection 2015. Review.
Wahl, S.E., McLane, L.E., Bercury, K.K., Macklin, W.B. and Wood, T.L. (2014) Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination. J. Neurosci. 34:4453-4465.
Rota, L.M., Albanito, L., Shin, M.E., Goyeneche, C.L., Shushanov, S., Gallagher, E.J., LeRoith, D., Lazzarino, D.A.* and Wood, T.L.* (2014) Inhibiting insulin-like growth factor receptor in mammary epithelium accelerates Wnt1-mediated tumorigenesis, canonical Wnt signaling and IGF-II/insulin receptor-A expression. Cancer Research 74(19): 1-12. *co-senior authors
Ziegler, A.N., Chidambaram, S., Forbes, B.E., *Wood, T.L. and *Levison, S.W. (2014) IGF-II and IGF-II analogs with enhanced insulin receptor-A binding affinity promote neural stem cell expansion. J. Biol. Chem. 289:4626-4633. *co-senior authors.
Ziegler, A.N., Levison, S.W. and Wood, T.L. (2014) Insulin and IGF receptor signaling in neural stem cell homeostasis. Nature Reviews Endocrinology, advance online publication 2 December 2014; doi:10.1038/nrendo.2014.208.
Wood, T.L., Bercury, K.K., Cifelli, S.E., Mursch, L.E., Min, J., Dai, J. and Macklin, W.B. (2013) mTOR: A link from the extracellular milieu to transcriptional regulation of oligodendrocyte development. ASN Neuro 5(1):63-79.
Simonishvili, S., Jain, M., Li, H., Levison, S.W. and Wood, T.L. (2013) Mechanisms for Bax-mediated death of oligodendrocyte progenitors in glutamate excitotoxicity and after perinatal hypoxia-ischemia. ASN- Neuro, Dec 23;5(5):e00131.
Min, J. and Wood, T.L. (2012) IGF-1 enhances S and G2/M phase progression in coordination with FGF-2 in oligodendrocyte progenitor cells. GLIA 60:1684-1695.


Courses Taught

GSND0596Q Professional Skills



Everything A Medical School Should Be - And More