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Department of Pharmacology, Physiology & Neuroscience

Jorge M. Serrador, Ph.D., M.Sc., B.Sc.

 

Medical Science Building (MSB)
185 South Orange Avenue Room I619
Newark , NJ 07101
Phone: (973) 972-8057
Fax: (973) 972-7950
 
 

Biography

Education

Ph.D., 2000, The University of Western Ontario, Kinesiology
M.Sc., 1997, University of Waterloo, Kinesiology
B.A., 1993, University of Waterloo, Psychology (Honours)
B.Sc., 1992, University of Waterloo, Physiology

 

Curriculum Vitae

View CV

 

Languages

Portugese

 

Publications

Relevant Publications:

Castro P, Serrador JM, Rocha I, Sorond F, Azevedo E. Efficacy of Cerebral Autoregulation in Early Ischemic Stroke Predicts Smaller Infarcts and Better Outcome. Front Neurol. 2017 Mar 24;8:113. doi: 10.3389/fneur.2017.00113. eCollection 2017.
Serrador JM, Freeman R. Enhanced cholinergic Activity Improves Cerebral Blood Flow During Orthostatic Stress. Front Neurol. 2017 Mar 20;8:103. doi: 10.3389/fneur.2017.00103. eCollection 2017.
Haber YO, Chandler HK, Serrador, JM. Symptoms Associated with Vestibular Impairment in Veterans with Posttraumatic Stress Disorder. PLoS One. 2016 Dec 29;11(12):e0168803. doi: 10.1371/journal.pone.0168803. eCollection 2016.
Breen PP, Serrador JM, O'Tuathail C, Quinlan LR, McIntosh C, Ă“Laighin G. Peripheral tactile sensory perception of older adults improved using subsensory electrical noise stimulation. Med Eng Phys. 2016 Aug;38(8):822-5. doi: 10.1016/j.medengphy.2016.05.015. Epub 2016 Jun 15.
McAndrew LM, Chandler HK, Serrador JM, Quigley KS, Natelson B, Lange G. Comparison of the Functional Health Limitations of Veterans Deployed to Iraq or Afghanistan to Veterans Deployed to Desert Shield/Storm with Chronic Fatigue Syndrome. DOI: 10.1080/21635781.2016.1175980, 2016.
Evans JM, Ribeiro LC, Moore FB, Wang S, Zhang Q, Kostas V, Ferguson CR, Serrador J, Falvo M, Stenger MB, Goswami N, Rask JC, Smith JD, Knapp CF. Hypovolemic men and women regulate blood pressure differently following exposure to artificial gravity. Eur J Appl Physiol. 2015 Dec;115(12):2631-40.
Breen PP, Ă“Laighin G, McIntosh C, Dinneen SF, Quinlan LR, Serrador JM. A new paradigm of electrical stimulation to enhance sensory neural function. Med Eng Phys. 2014 Aug;36(8):1088-91
Evans JM, Stenger MB, Ferguson CR, Ribiero LC, Zhang Q, Moore FB, Serrador JM, Smith JD, Knapp CF. Mechanisms of Orthostatic Tolerance Improvement Following Artificial Gravity Exposure Differ between Men and Women. http://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/20140003861.pdf
Haack M, Serrador JM, Cohen D, Simpson N, Meier-Ewert H, Mullington JM. Increasing Sleep Duration to Lower Beat-to-Beat Blood Pressure: A Pilot Study. J Sleep Res. 2013 Jun; 22(3): 295-304.
Falvo MJ, Serrador JM, McAndrew LM, Chandler HK, Lu SE, Quigley KS. A Retrospective Cohort Study of U.S. Service Members Returning from Afghanistan and Iraq: Is Physical Health Worsening Over Time? BMC Public Health. 2012 Dec 28; 12:1124.

 

Courses Taught

CBNP5033Q Systems Neuroscience

CBNP5165Q Fnds Integr Human Phys


Current Research

Improving cognitive function in veterans with Gulf War Illness by improving cerebral vascular function
Aim 1: Explain the cognitive impairment Veterans with GWI experience through the reduced capacity of the cerebrovasculature to dilate.
Aim 2: Determine if low cerebrovascular reactivity can be restored by blocking COX improving cognitive function.

Post Exertion Malaise in GWI: Brain Autonomic and Behavioral Interactions
The proposed research studies will determine whether interactions among central nervous, autonomic, and immune systems explain symptoms at
baseline and the worsening of symptoms that occur following exercise challenge (i.e., post-exertion malaise).

Diagnosis of Late-stage, Early-onset, Small-fiber Polyneuropathy
Aim 1: Improving diagnosis: Develop and validate simpler SFPN tests for general use with Gulf War veterans.
Aim 2: Developing genetic tests: Develop and validate sequencing based tests for polymorphisms in SFPN-associated genes for use in GW
veterans and civilians with L/E/SFPN.

SARA - Sensorimotor Assessment and Rehabilitation Apparatus
Aim 1: Correlate behavioral measure of ocular misalignment from otolith damage against gold standard measures of otolith function in an mTBI,
vestibular deficit.
Aim 2: Investigate difference in dynamic visual acuity to distinguish vestibular oculomotor from visual oculomotor control dysfunction.
Aim 3: Predict who with vestibular hypofunction will respond well to vestibular rehabilitation intervention.

Use of a portable stimulator to treat Gulf War Illness
Aim 1: Determine the level of vestibular dysfunction in a group of Veterans with Gulf War Illness.
Aim 2: Determine the effectiveness of subsensory electrical stimulation in a population of Veterans with vestibular dysfunction to improve
balance function.

Treatment of vestibular dysfunction using a portable stimulator
The major goal of this award is to determine if the use of stochastic noise electrical stimulation can improve vestibular function in those
with vestibular loss. In addition, we will develop a portable stimulator that can be used as a new restorative device.



 

 

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