Herbig Publications

Selected Publications

  • Patel, P., Suram, A., Mirani, N., Bischof, O., Herbig, U.2016 Derepression of hTERT Gene Expression Promotes Escape from Oncogene-Induced Cellular Senescence. PNAS; in press
  • Boccardi, V., Razdan, N., Kaplunov, J., Mundra, JJ., Kimura, M., Aviv, A., and Herbig, U. 2015. Stn1 is critical for telomere maintenance and long term viability of somatic human cells. Aging Cell 14:372
  • Suram A, Herbig U. 2014. The replicometer is broken: telomeres activate cellular senescence in response to genotoxic stresses. Aging Cell. 18. doi: 10.1111
  • Suram A, Kaplunov J, Patel PL, Ruan H, Cerutti A, Boccardi V, Fumagalli M, Di Micco R, Mirani N, Gurung RL, Hande MP, d'Adda di Fagagna F, Herbig U. 2012. Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. The EMBO Journal. 31: 2839-51
  • Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, Kaplunov JM, Bucci G, Dobreva M, Matti V, Beausejour CM, Herbig U, Longhese MP, d'Adda di Fagagna F. 2012. Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nature Cell Biology 14: 355-65
  • Benhamed M, Herbig U, Ye T, Dejean A, Bischof O.2012. Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells. Nature Cell Biology 14: 266-75
  • Jeyapalan, JC., Ferreira, M., Sedivy, JM., and Herbig, U. 2007. Accumulation of Senescent Cells in Mitotic Tissue of Aging Primates. Mechanisms of Ageing and Development. 128:36-44
  • Herbig, U., Ferreira, M., Condel, L., Carey, D. and Sedivy, J.M. 2006. Cellular senescence in aging primates. Science 311:1257