Clinical Research

Glaucoma

 

A double-masked, randomized, multi-center, active-controlled, parallel group, 6-month study with a 3-month interim analysis assessing the ocular hypotensive efficacy and safety of AR-13324 Ophthalmic Solution, 0.02% QD compared to Timolol Maleate Ophthalmic Solution, 0.5% BID in patients with elevated intraocular pressure Rho Kinase Elevated Intraocular Pressure Treatment Trial; (ROCKET 4).

Investigator: Albert S. Khouri, MD
Co-investigators: Robert D Fechtner, MD
Condition: Glaucoma patients

Status: Open

Lunar 770: Clinical trial comparing efficacy of a new glaucoma medication to timolol

Investigator: Albert S. Khouri, MD

Status: Data Analysis

The current study is designed to permit a valid comparison of the diurnal Intra-Ocular pressure lowering effect of BOL-303259-X 0.024% (study drug) once daily with a positive control of known efficacy, timolol maleate 0.5%, in subjects with Open Angle Glaucoma or Ocular Hypertension, and to demonstrate long-term
safety with BOL-303259-X 0.024% (study drug) once daily.

The NJ Health Foundation Telemedicine Trial: Feasibility of Tele-presence in Glaucoma

Investigator: Albert S. Khouri, MD
Co-investigators:Ben Szirth, PhD

Status: Active Enrollment

Telemedicine allows screening of subjects with limited access to eye care. Failure of screenees to come for full examination was identified as a serious problem (Hoffberger program, Am J Ophthalmol 2002). Telepresence should allow a single physician access to screenees in real time. We aim to test the technical feasibility of developing a system for telepresence in ophthalmology that will allow a physician real time access to patient data and images. This system can be applied during telemedicine for glaucoma and other vision threatening diseases.

Software Analysis of Optic nerve and Nerve Fiber Layer during Tele-screening

Investigator: Albert S. Khouri, MD, Ben Szirth PhD

Status: Active Enrollment

To test the applications of digital optic nerve imaging with image analysis using software filters and optical coherence tomography during screening for vision threatening diseases.

Outcomes of complex cataract surgery

Investigator: Albert S. Khouri, MD

Status: Retrospective review

The purpose of this study is to study visual, intraocular pressure and other outcomes of complex cataract surgery performed by faculty and residents. The analyses will include the effects of iris manipulation and other intra-operative interventions on outcomes.

Long term outcomes of childhood glaucomas

Investigator: Albert S. Khouri, MD

Status: Retrospective review

This study is a review of a large data base of patients who have presented to the Institute of Ophthalmology and Visual Science, a primary regional referral center for rare diseases such as childhood glaucoma. This study will investigate the presenting symptoms and exam findings of patients, as well as their treatment and long-term follow up. It will assess visual outcomes of the therapy as well as other parameters such as intraocular pressure, corneal diameter, and number of medications used at each time point, to evaluate the effectiveness of the treatments.

Intraocular pressure outcomes in patients with glaucoma

Investigator: Albert S. Khouri, MD

Status: Retrospective review

This study seeks to study the effectiveness of intraocular pressure control in patients diagnosed, treated, and followed-up with primary open-angle glaucoma at a tertiary care center. This includes a cohort of subjects with advanced glaucoma (based on optic nerve damage and visual field loss criteria). The study also investigates medical treatment parameters, side effects and systemic implications of topical therapy.

STOP Glaucoma Pilot Enrollment Survey

Investigator: Robert D fechtner, MD; Subinvestigator: Albert S Khouri, MD

Status:Active

Improving the Success of Laser Treatment for Glaucoma: Effect of Ocular Pigmentation

Cost Analysis of Glaucoma Surgery

Efficacy and Safety of Bimatoprost Sustained Release (SR) in Patients with Open-Angle Glaucoma or Ocular Hypertension

The AGS Second Aqueous Shunt Implant Versus TransScleral Cyclophotocoagulation Treatment Study (ASSISTS)

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