Clinical Research
Retina and Vitreous
RUSH Study: Inherited Retinal Diseases
Investigator: Marco Zarbin, MD
Co-Investigator: Neelakshi Bhagat, MD, MPH
Thome Study: Improving Cell-Based Therapy for Age-Related Macular Degeneration
Investigator: Marco Zarbin, MD
DRCRnet Protocol M: Effect of Diabetes Education During Retinal Ophthalmology Visits on Diabetes Control
Investigator: Neelakshi Bhagat, MD, MPH
Condition: Diabetes
Status: Closed to Enrollment
This study is designed to evaluate if giving additional educational information about diabetes and diabetic eye disease during an examination of the retina can help patients better manage their diabetes. This clinical trial is sponsored by the National Institute of Health (NIH) through a grant to the Diabetic Retinopathy Clinical Research Network (DRCRnet).
For more information, please contact: Neelakshi Bhagat, MD, MPH at (973) 972-2032 or Catherine Fay at (973) 972-2052.
DRCRnet Protocol R: Topical NSAIDs on Eyes with Non-Central Involved DME
Investigator: Neelakshi Bhagat, MD, MPH
Condition: Diabetic Macular Edema (DME)
Status: Closed to Enrollment
The purpose of this research is to evaluate the use of topical non-steroidal anti-inflammatory drugs (NSAIDs) to treat diabetic macular edema. This study tests the effectiveness of NSAID eye drops compared to placebo drops in eyes with non-central involved diabetic macular edema. This clinical trial is sponsored by the National Institutes of Health (NIH) through a grant to the Diabetic Retinopathy Clinical Research Network (DRCRnet).
For more information, please contact: Neelakshi Bhagat, MD, MPH at (973) 972-2032 or Catherine Fay at (973) 972-2052.
AREDS2: Age-Related Eye Disease Study 2
Investigator: Neelakshi Bhagat, MD, MPH
Condition: Age-Related Macular Degeneration (AMD)
Status: Closed to Enrollment
In previously diagnosed participants with age-related macular degeneration (AMD), this clinical trial evaluates the effect of oral nutritional supplements - lutein and zeaxanthin and/or omega-3 long-chain polyunsaturated fatty acids, specifically, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on the development and progression of AMD. An additional goal of this study is to evaluate which concentrations of EPA and DHA are most effective in reducing the risk of progression to advanced AMD. This clinical trial is funded by the National Eye Institute.
For more information, please contact: Neelakshi Bhagat, MD, MPH at (973) 972-2032 or Catherine Fay at (973) 972-2052.
Rubeosis Trial: Use of Ranibizumab to Treat Rubeosis in
Diabetics Prior to Cataract Surgery
Investigator: Neelakshi Bhagat, MD, MPH
Condition: Proliferative Diabetic Retinopathy (PDR) and Dense Cataract
Status: Closed to enrollment/ Data Analyssi Only
The purpose of this trial is to treat proliferative diabetic retinopathy (PDR) expeditiously rather than following cataract surgery. We expect that such treatment will also reduce the bleeding complications encountered during cataract surgery in patients with active rubeosis resulting from PDR. This study is sponsored by Genentech, Inc.
For more information, please contact: Neelakshi Bhagat, MD, MPH at (973) 972-2032 or Catherine Fay at (973) 972-2052.
NJ 725 Study: Inflammatory Biomarkers and Progression of Diabetic Retinopathy
Condition: Diabetic Retinopathy
Status: Ongoing
The purpose of the study is to identify inflammatory biomarkers associated with development and/or progression of diabetic retinopathy in African Americans with type 1 diabetes mellitus. This clinical trial is supported by a grant from the National Eye Institute
Genes Associated with Diabetes and Diabetic Retinopathy in Type 1 Diabetic African Americans
Condition: Diabetes/Diabetic Retinopathy
Status: Closed to enrollment/data analysis
Neural Stability After Retinal Detachment
Progression of Diabetic Retinopathy in Type-1 African Americans
Visual Outcomes of Diabetic Traction
Investigator: Neelakshi Bhagat, MD, MPH
Repair of Retinal Detachments with Silicone Oil Tamponade
Investigator: Neelakshi Bhagat, MD, MPH
Comparative Analysis of Intraocular Pressure Measurement Techniques in Surgical Retina Clinic
Retrospective review of post-surgical endophthalmitis cases
Investigator: Neelakshi Bhagat, MD, MPH
Bleb-related endophthalmitis; a 10-year review
Investigator: Neelakshi Bhagat, MD, MPH
Use of silicone oil for complex retinal detachment cases
Investigator: Neelakshi Bhagat, MD, MPH
Use of anti-VEGF drugs for neo-vascular glaucoma
Investigator: Neelakshi Bhagat, MD, MPH
Non-arteritic anterior ischemic optic neuropathy after retinal detachment repair
Investigator: Neelakshi Bhagat, MD, MPH
The purpose of the study is to identify genes associated with diabetes or diabetic retinopathy in African Americans with type 1 diabetes. This study is funded by a grant from the University of Cambridge, United Kingdom
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