Clinical Research

Cornea and Uveitis

Study Assessing Double-Masked Uveitis Treatment (SAKURA)

Condition: Non-Infectious Intermediate, Posterior or Pan-Uveitis

Status: Active Enrollment

Non-infectious uveitis is an autoimmune disease that causes re-occurring inflammation of the eye. Symptoms may include vision loss, redness of the eye, blurred vision, and ocular pain. Uveitis is one of the leading causes of blindness worldwide. This clinical trial investigates three different doses of intra-ocular injections of DE-109 (sirolimus), for the treatment of active, non-infectious posterior, intermediate or pan- uveitis. This study is sponsored by Santen, Inc.

For more information about the LX211-11 research study, please contact: David S. Chu, MD at (973) 972-2064; Kathryn Boschert, MS at (973) 972-8308; or  Amanda Ribeiro, RN at (973) 972-2074.

LX 211-11: Efficacy and Safety of Voclosporin to Treat Active Noninfectious Uveitis

Investigator: David S. Chu, MD

Condition: Non-Infectious Intermediate, Posterior or Pan-Uveitis

Status: Closed to Enrollment

 

Non-infectious uveitis is an autoimmune disease that causes re-occurring inflammation of the eye. Symptoms may include vision loss, redness of the eye, blurred vision, and ocular pain. Uveitis is one of the leading causes of blindness worldwide. The LX211-11 research study is evaluating the use of LX211(voclosporin), an investigational immunosuppressive agent, for its ability to control active inflammation associated with uveitis. LX211 is taken in soft gelatin capsule form and has been studied in over 550 patients worldwide. This study is sponsored by Lux BioSciences, Inc.

For more information about the LX211-11 research study, please contact: David S. Chu, MD at (973) 972-2064; Kathryn Boschert, MS at (973) 972-8308; or  Amanda Ribeiro, RN at (973) 972-2074.

Collagen Cross-Linking in the Treatment of Keratoconus

Investigator:Peter S. Hersh, MD

Condition: Keratoconus and Post-Refractive Corneal Ectasia

Status: On-Going

 

Corneal collegen cross linking is a new technique that makes use of ultraviolet light combined with riboflavin. The technique is designed to strengthen the cornea for the purpose of decreasing the progression of corneal ectatic diseases, e.g., keratoconus and post-refractive corneal ectasia. Part of this study involves investigating the use of hypotonic vs. isotonic riboflavin solution to see what effects are imposted on corneal thickness.

Corneal Collagen Crosslinking and Intracorneal Ring Segments (Intacs) for Keratoconus: A Randomized Study of Concurrent Versus Sequential Treatments (Hersh)

Penetrating Keratoplasty Elevation of Intraocular Pressure

Surgical Outcomes of Pterygium Excision with Conjunctival Autograft

For more information about this and related research study, please contact: Peter S. Hersh, MD or Kathryn S. Pokorny, PhD.

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