This course will help bridge the gap between science theory and practice in modern pharmaceutical and biotechnology business using major blockbuster drug launches over the past 20 years as examples. Each class will focus on a single therapeutic area (eg, Type 2 diabetes, cervical cancer, multiple sclerosis, GERD) and will be divided into two sections: first a review of relevant underlying pharmacological principles (eg., pharmacodynamics/mechanism of action, pharmacokinetics, toxicology, and clinical study data) followed by case examples of how these concepts were used to develop specific product marketing and educational campaigns to support product differentiation. This course provides the student with a fundamental in-depth understanding of current concepts of cell biology and of basic types of pathological processes at the cellular level. Microscopic, submicroscopic, and molecular models of both normal and diseased cells will be critically examined and discussed. Special attention will be given to normal and pathological changes associated with cellular organelles and with alterations in their structure and activity in various disease states. Cellular processes such as apoptosis and cell death, DNA damage and repair, telomere function and dysfunction, melanocyte function in the skin and consequences of its dysfunction, cellular changes which occur during aging of the skin, and the effects of viruses on cell structure and function will be discussed. Click here for fall 2023 syllabus.
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