Student Publications

2015

Yarosh CA, Iacona JR, Lutz CS, Lynch KW. 2015. PSF: nuclear busy-body or nuclear facilitator? Wiley Interdiscip Rev RNA. Jul;6(4):351-67. doi: 10.1002/wrna.1280. Epub 2015 Apr 1.

Geissler, J.R., Bajaj, D., & Fritton, J.C.; “American Society of Biomechanics Journal of Biomechanics Award 2013: Cortical bone tissue mechanical quality and biological mechanisms possibly underlying atypical fractures; Journal of Biomechanics, 48:883-94, 2015.

Dhawan, P. Wei, R., Sun, C., Gombart, A.F. Koeffler, H. P., Diamond, G. and Christakos, S. C/EBPα and the vitamin D receptor cooperate in the regulation of cathelicidin in lung epithelial cells. J Cell Physiol 230: 464-472, 2015.

Li W, You B, Hoque M, Luo W, Park JY, Ji Z, Zheng D, Gunderson SI, Kalsotra A, Manley JL, Tian B. (2015). Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation. PLoS Genet. 11(4):e1005166.

Servatius RJ, Avcu P, Ko N, Jiao X, Beck KD, Minor TR, Pang KC. Avoidance expression in rats as a function of signal-shock interval: strain and sex differences. Front Behav Neurosci. 2015 Jul 6;9:168. doi: 10.3389/fnbeh.2015.00168. eCollection 2015.

Myers, C. E., Kostek, J. A., Ekeh, B., Sanchez, R., Ebanks-Williams, Y., Krusznis, A. L., Weinflash, N., & Servatius, R. (2015/in press). Watch what I do, not what I say I do: Computer-based “avatars” to assess behavioral inhibition, a vulnerability factor for anxiety disorders. Computers in Human Behavior, to appear. PMID: in process; PMCID: in process.

Badheka D, Borbiro I, Rohacs T. Transient receptor potential melastatin 3 is a phosphoinositide-dependent ion channel J Gen Physiol. 2015 Jul;146(1):65-77. doi: 10.1085/jgp.201411336. PMID: 26123195

Borbiro I, Badheka D, Rohacs T. Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides. Sci Signal. 2015 Feb 10;8(363):ra15. doi: 10.1126/scisignal.2005667. PMID: 25670203

Kota K, Kuzhikandathil EV, Afrasiabi M, Lacy B, Kontoyianni M, Crider AM, Song D. Identification of key residues involved in the activation and signaling properties of dopamine D3 receptor. Pharmacol Res. 2015 Jun 23;99:174-184. doi: 10.1016/j.phrs.2015.05.016. [Epub ahead of print] PMID: 26116441

Pang KCH, Sinha S, Avcu P, Roland JJ, Nadpara N, Pfister BJ, Long M, Santhakumar V, Servatius RJ. (2015) Long-lasting suppression of acoustic startle response following mild traumatic brain injury. Journal of Neurotrauma. 32:801–810 (June 1) DOI:10.1089/neu.2014.3451.

Li Y*, Korgaonkar A*, Swietek B , Wang J, Elgammal FS, Elkabes, S, Santhakumar V. (2015) Toll-like receptor 4  augments mossy cell AMPA currents and contributes to NMDA receptor-independent increase in dentate excitability after brain injury. Neurobiology of Disease. Feb;74:240-53 DOI: 10.1016/j.nbd.2014.11.021* Equal Contribution.

Yu J, Swietek B, Proddutur A, Santhakumar V (2015) Dentate total molecular layer interneurons mediate cannabinoid-sensitive inhibition. Hippocampus. Jan 20. DOI: 10.1002/hipo.22419.

Wahab RA, Neuberger EJ, Lyeth BG, Santhakumar V, Pfister BJ (2015) Percussion Injury Device for the Precise Control of Injury Parameters. Journal of Neuroscience Methods. Jun 15;248:16-26. DOI: 10.1016/j.jneumeth.2015.03.010

Proddutur A, Santhakumar V. 2015. (in press) Marching Towards a Seizure: Spatio-Temporal Evolution of Preictal Activity. Epilepsy Currents

Guiro, K., Patel, S.A., Greco, S.J., Rameshwar, P., & Arinzeh, T.L.; “Investigating breast cancer cell behavior using tissue engineering scaffolds”; PLoS One, 10(3):e0118724, 2015.

Sheynin, J., Moustafa, A.A., Beck, K.D., Servatius, R.J., & Myers, C.E.; “Testing the role of reward and punishment sensitivity in avoidance behavior: a computational modeling approach”; Behav Brain Res., 283:121-38, 2015.

Kung, F., Wang, J., Perez-Castillejos, R., & Townes-Anderson, E.; “Position along the nasal/temporal plane affects synaptic development by adult photoreceptors, revealed by micropatterning”; Integr Biol (Camb)., 7(3):313-23, 2015.

Patel CR, Douard V, Yu S, Tharabenjasin P, Gao N, Ferraris RP. Fructose-induced increases in expression of intestinal fructolytic and gluconeogenic genes are regulated by GLUT5 and KHK. Am J Physiol Regul Integr Comp Physiol. 2015 Jun 17:ajpregu.00128.2015. doi: 10.1152/ajpregu.00128.2015. [Epub ahead of print] PMID: 26084694

Patel C, Douard V, Yu S, Gao N, Ferraris RP. Transport, metabolism, and endosomal trafficking-dependent regulation of intestinal fructose absorption.FASEB J. 2015 Jun 12. pii: fj.15-272195. [Epub ahead of print] PMID: 26071406

Sehgel, N.L., Sun, Z., Hong, Z., Hunter, W.C., Hill, M.A., Vatner, D.E., Vatner, S.F., & Meininger, G.A.; “Augmented vascular smooth muscle cell stiffness and adhesion when hypertension is superimposed on aging’; Hypertension, 65(2):370-7, 2015.

Jain, N., & Lee, E.J.; “Islet endothelial cells derived from mouse embryonic stem cells”; Cell Transplant., [Epub ahead of print, In Press] 2015.

Huang, G.P., Shanmugasundaram, S., Masih, P., Pandya, D., Amara, S., Collins, G., & Arinzeh, T.L.; “An investigation of common crosslinking agents on the stability of electrospun collagen scaffolds”; J Biomed Mater Res A. 103(2):762-71, 2015.

Nguyen, K.H., Xu, F., Flowers, S., Williams. E.A., Fritton, J.C., & Moran, E.; “SWI/SNF-mediated lineage determination in mesenchymal stem cells confers resistance to osteoporosis”; Stem Cells, doi: 10.1002/stem.2064 [Epub ahead of print, In Press] 2015.

Pang, K.C., Sinha, S., Avcu, P., Roland, J.J., Nadpara, N., Pfister, B.J., Long, M., Santhakumar, V., & Servatius, R.J.; “Long-lasting suppression of acoustic startle response after mild traumatic brain injury”; J Neurotrauma., 32(11):801-10, 2015.

Bajaj, D., Geissler, J.R., Allen, M.R., Burr, D.B., & Fritton, J.C.; “Response to Courtney et al”; Bone, doi: doi: 10.1016/j.bone.2015.03.007 [Epub ahead of print, In Press] 2015.

Nolan, K.J., Yarossi, M., & Mclaughlin, P.; “Changes in center of pressure displacement with the use of a foot drop stimulator in individuals with stroke”; Clin Biomech (Bristol, Avon)., doi: 10.1016/j.clinbiomech.2015.03.016 [Epub ahead of print, In Press] 2015.

Li, Y., Korgaonkar, A.A., Swietek, B., Wang, J., Elgammal, F.S., Elkabes, S., & Santhakumar, V.; “Toll-like receptor 4 enhancement of non-NMDA synaptic currents increases dentate excitability after brain injury”; Neurobiol Dis., 74:240-53, 2015.

Fluet, G.G., Merians AS, Qiu, Q., Rohafza, M., VanWingerden A.M., & Adamovich, S.V.; “Does training with traditionally presented and virtually simulated tasks elicit differing changes in object interaction kinematics in persons with upper extremity hemiparesis?” Top Stroke Rehabil., 22(3):176-84, 2015.

Hreha, J., Wey, A., Cunningham, C., Krell, E.S., Brietbart, E.A., Paglia, D.N., Montemurro, N.J., Nguyen, D.A., Lee, Y.J., Komlos, D., Lim, E., Benevenia, J., O'Connor, J.P., & Lin, S.S.; “Local manganese chloride treatment accelerates fracture healing in a rat model”; J Orthop Res., 33(1):122-30, 2015.

Liporace, F.A., Brietbart, E.A., Yoon, R.S., Doyle, E., Paglia, D.N., & Lin, S.S.; “The effect of locally delivered recombinant human bone morphogenetic protein-2 with hydroxyapatite/tri-calcium phosphate on the biomechanical properties of bone in diabetes-related osteoporosis”; J Orthop Traumatol., 16(2):151-9, 2015.

Schettino, L.F., Adamovich, S.V., Bagce, H., Yarossi, M., & Tunik, E.; “Disruption of activity in the ventral premotor but not the anterior intraparietal area interferes with on-line correction to a haptic perturbation during grasping”; J Neurosci., 35(5):2112-7, 2015.

Mitchell, M.D., Yarossi, M., Pierce, D.N., Garbarini, E.L., & Forrest GF.; “Reliability of surface EMG as an assessment tool for trunk activity and potential to determine neurorecovery in SCI”; Spinal Cord., 53(5):368-74, 2015.

Guito, J, DM Lukac (2015) KSHV Reactivation and Novel Implications of Protein Isomerization on Lytic Switch Control. Viruses 7: 72-109.

Subramanian S, Mitchell A, Yu W, Snyder S, Uhrich K, O'Connor JP . 2015. Salicylic Acid-Based Polymers for Guided Bone Regeneration Using Bone Morphogenetic Protein-2.Tissue Eng Part A. 2015 Jul;21(13-14):2013-24. doi: 10.1089/ten.TEA.2014.0455. Epub 2015 Apr 29.

Cottrell JA, Lin HN, O'Connor JP. 2015. Method for measuring lipid mediators, proteins, and messenger RNAs from a single tissue specimen. Anal Biochem. 2015  Jan 15;469:34-42. doi: 10.1016/j.ab.2014.10.004. Epub 2014 Oct 20.

Strauss, K.A., Jinks, R.N., Puffenberger, E.G. Venkatesh, S., Singh, K., Cheng, I., Mikita, N., Thilagavathi, J., Lee, J., Sarafianos, S., Benkert, A., Koehler, A., Zhu, A., Trovillion.V., McGlincy, M., Morlet, T., Deardorff, M., Innes, A.M., Prasad, C., Chudley, A.E., Lee, I.N.W., and Suzuki, C.K.  CODAS syndrome is associated with mutations of LONP1 encoding mitochondrial AAA+ Lon protease.  Am. J. Hum. Genet. . 96, 121–135 (2015).

Fotinos, A, Fritz, DT, Lisica, S, Liu, Y, Rogers, M. B. 2015. Competing Repressive Factors Control Bone Morphogenetic Protein 2 (BMP2) in Mesenchymal Cells Journal of Cellular Biochemistry (in press).

Rogers, M. B., TA Shah, NN Shaikh. 2015. Turning Bone Morphogenetic Protein 2 (BMP2) On and Off in Mesenchymal Cells. Journal of Cellular Biochemistry (in press)

2014

Sheng, Z., Santiago, A.M., Thomas, M.P. and V.H. Routh. Metabolic regulation of lateral hypothalamic glucose-inhibited orexin neurons may influence midbrain reward neurocircuitry. Mol. Cell. Neurosci. 62:30-41, 2014.

David BT, Sampath S, Dong W, Heiman A, Rella CE, Elkabes S, Heary RF. A toll-like receptor 9 antagonist improves bladder function and white matter sparing in spinal cord injury. J Neurotrauma. 2014 Nov 1;31(21):1800-6. doi: 10.1089/neu.2014.3357. Epub 2014 Aug 25. PMID: 24936867

Mustaev, A., Malik, M., Zhao, X., Kurepina, N., Luan, G., Oppegard, L.M., Hiasa, H., Marks, K.R., Kerns, R.J., Berger, J.M., and Drlica, K.  2014. Fluoroquinolone-gyrase-DNA complexes: two modes of drug binding. J. Biol. Chemistry 289: 12300-12312.

Li, L., Hong, Y., Luan, G.,  Mosel, M., Malik, M., Drlica, K., and Zhao, X. 2014. Ribosomal elongation factor-4 promotes cell death associated with lethal stress.  mBio 5:e01708

Drlica, K., Mustaev, A., Towle, T.R., Luan, G., Kerns, R.J. and Berger, J.M. 2014. Bypassing fluoroquinolone resistance with quinazolinediones: studies of drug-gyrase-DNA complexes having implications for drug design. ACS Chemical Biology 9:2895-2904.

Avcu, P., Jiao, X., Myers, C. E., Beck, K. D., Pang, K. C. & Servatius, R. J. (2014). Avoidance as expectancy in rats: Sex and strain differences in acquisition. Frontiers in Behavioral Neuroscience, 8:334. PMID 25339874; PMCID: PMC4186307.

Routh, V.H., Hao, L., Santiago, A.M., Sheng, Z. and C. Zhou. Hypothalamic glucose sensing: making ends meet. Front. Syst. Neuro. Doi 10.3389/fnsys.2014.00236.

Yu S, Nie Y, Knowles B, Sakamori R, Stypulkowski E, Patel C, Das S, Douard V, Ferraris RP, Bonder EM, Goldenring JR, Ip YT, Gao N. TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J. 2014 Sep 1;33(17):1882-95. doi: 10.15252/embj.201487888. Epub 2014 Jul 24.

Douard V, Patel C, Lee J, Tharabenjasin P, Williams E, Fritton JC, Sabbagh Y, Ferraris RP. Chronic high fructose intake reduces serum 1,25 (OH)2D3 levels in calcium-sufficient rodents. PLoS One. 2014 Apr 9;9(4):e93611. doi:10.1371/journal.pone.0093611. eCollection 2014.

Fotinos, A, Nagarajan, N, Adriano S. Martins, AS, Fritz, DT, Garsetti, D, Lee, AT, Hong, CC, and Rogers, MB. 2014. Bone Morphogenetic Protein-focused Strategies to Induce Cytotoxicity in Lung Cancer Cells, Anticancer Research, 34 (5): 2095-2104

M.A, Lea, J. Pourat, R. Patel and C. desBordes. 2014. Inhibition of growth of colon cancer cells by compounds affecting AMPK activity. World J. Gastrointest. Oncol., 6, 244-252.

Guito, J, A Gavina, D Palmeri, and DM Lukac (2014). The cellular peptidyl-prolyl cis/trans isomerase Pin1 regulates reactivation of Kaposi's sarcoma-associated herpesvirus from latency. J Virol 88:547-558.

Shin, HJ, DeCotiis, J, Giron, M, Palmeri, D and DM Lukac. (2014), “Histone Deacetylase Classes I and II Regulate Kaposi’s Sarcoma-Associated Herpesvirus Reactivation.” J Virol 88:1281-1292.

Alagappan D, Ziegler AN, Chidambaram S, Min J, Wood TL, Levison SW. 2014. Insulin-Like Growth Factor Receptor Signaling is Necessary for Epidermal Growth Factor Mediated Proliferation of SVZ Neural Precursors in vitro Following Neonatal Hypoxia-Ischemia. Front Neurol. 2014 May 26;5:79. doi: 10.3389/fneur.2014.00079. eCollection 2014.

Ziegler AN, Chidambaram S, Forbes BE, Wood TL, Levison SW. 2014. Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion. J Biol Chem. 2014 Feb 21;289(8):4626-33. doi: 10.1074/jbc.M113.537597. Epub 2014 Jan 7.

Tsou WI, Nguyen KQ, Calarese DA, Garforth SJ, Antes AL, Smirnov SV, Almo SC, Birge RB, Kotenko SV. 2014. Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation. J Biol Chem. 2014 Sep 12;289(37):25750-63. doi: 10.1074/jbc.M114.569020. Epub 2014 Jul 29.

Kimani SG, Geng K, Kasikara C, Kumar S, Sriram G, Wu Y, Birge RB. 2014. Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity. Front Immunol. 2014 Nov 10;5:566. doi: 10.3389/fimmu.2014.00566. eCollection 2014. Review.

Sriram G, Jankowski W, Kasikara C, Reichman C, Saleh T, Nguyen KQ, Li J, Hornbeck P, Machida K, Liu T, Li H, Kalodimos CG, Birge RB. 2014. Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk. Oncogene. 2014 Nov 10. doi: 10.1038/onc.2014.361. [Epub ahead of print]

Nguyen KQ, Tsou WI, Calarese DA, Kimani SG, Singh S, Hsieh S, Liu Y, Lu B, Wu Y, Garforth SJ, Almo SC, Kotenko SV, Birge RB. 2014. Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity. J Biol Chem. 2014 Sep 12;289(37):25737-49. doi: 10.1074/jbc.M114.570838. Epub 2014 Jul 29.

Cornett AL, Lutz CS. 2014. Modulation of COX-2 expression by miR146a. RNA, 20:1419-30. doi: 10.1261/rna.044149.113. Epub 2014 Jul 21. (2014).

Vaziri B, Wu H, Dhawan AP, et al. 2014. MIRD Pamphlet No. 25: MIRDcell V2.0 Software Tool for Dosimetric Analysi of Biologic Response of Multicellular Populations. J Nucl Med. 2014;55:1557-1564.

Pasternack JB, Domogauer JD, Khullar A, Akudugu JM, Howell RW. 2014. The advantage of antibody cocktails for targeted alpha therapy depends on specific activity. J Nucl Med. 2014;55:2012-2019.

Kumar S, Fajardo JE, Birge RB, Sriram G. 2014. Crk at the quarter century mark: perspectives in signaling and cancer. J Cell Biochem. 2014 May;115(5):819-25. doi: 10.1002/jcb.24749.

Ordek, G., Proddutur, A., Santhakumar, V., Pfister, B.J., & Sahin, M.; “Electrophysiological monitoring of injury progression in the rat cerebellar cortex”; Front Syst Neurosci., 8:197, 2014.

Siriwardane, M. L., DeRosa, K., Collins, G. & Pfister, B. J.; “Controlled formation of cross-linked collagen fibers for neural tissue engineering applications”; Biofabrication, 6: 015012, 2014.

Skop N.B., Calderon, F., Cho, C.H., Gandhi, C.D., & Levison, S.W.; “Improvements in biomaterial matrices for neural precursor cell transplantation”; Acta Biomater., Mol Cell Ther., 2:19, 2014.

Sheynin, J., Beck, K.D., Servatius, R.J., & Myers, C.E.; “Acquisition and extinction of human avoidance behavior: attenuating effect of safety signals and associations with anxiety vulnerabilities”; Front Behav Neurosci., 8:323, 2014.

Sheynin, J., Beck, K.D., Pang, K.C., Servatius, R.J., Shikari, S., Ostovich, J., & Myers, C.E.; “Behaviourally inhibited temperament and female sex, two vulnerability factors for anxiety disorders, facilitate conditioned avoidance (also) in humans”; Behav Processes., 103:228-35, 2014.

Yarossi, M., Adamovich, S.V., & Tunik, E.; “Sensorimotor cortex reorganization in subacute and chronic stroke: A neuronavigated TMS study”; Conf Proc IEEE Eng Med Biol Soc., 2014:5788-91, 2014.

Bajaj, D., Geissler, J.R., Allen, M.R., Burr, D.B., & Fritton, J.C.; “The resistance of cortical bone tissue to failure under cyclic loading is reduced with alendronate”; Bone, 64:57-64, 2014.

Karunakaran, K., Abbruzzese, K., Xu, H., Ehrenberg, N., & Foulds, R.A.; ”Haptic proprioception in a virtual locomotor task”; Conf Proc IEEE Eng Med Biol Soc., 2014:3594-7, 2014.

Neuberger, E.J., Abdul Wahab , R., Jayakumar, A., Pfister, B.J., & Santhakumar, V.; “Distinct effect of impact rise times on immediate and early neuropathology after brain injury in juvenile rats”; J Neurosci Res., 92(10):1350-61, 2014.

Rohafza, M., Fluet, G.G., Qiu, Q., & Adamovich, S.V.; ”Correlation of reaching and grasping kinematics and clinical measures of upper extremity function in persons with stroke related hemiplegia”; Conf Proc IEEE Eng Med Biol Soc., 2014: 3610-3, 2014.

Guo, Y., Foulds, R.A., Adamovich, S.V., & Sahin, M.; “Encoding of forelimb forces by corticospinal tract activity in the rat”; Front Neurosci. 8:62, 2014.

Jaswal, R., Gohel, S., Biswal, B.B., & Alvarez, T.L.; “Task-modulated coactivation of vergence neural substrates.” Brain Connect., 4(8):595-607, 2014.

Alvarez, T.L., Jaswal, R., Gohel, S., & Biswal, B.B.; “Functional activity within the frontal eye fields, posterior parietal cortex, and cerebellar vermis significantly correlates to symmetrical vergence peak velocity: an ROI-based, fMRI study of vergence training”; Front Integr Neurosci., 8:50, 2014.

Androwis, G.J., Michael, P.A., Strongwater, A., & Foulds, R.A.; “Estimation of intrinsic joint impedance using quasi-static passive and dynamic methods in individuals with and without Cerebral Palsy”; Conf Proc IEEE Eng Med Biol Soc., 2014:4403-6, 2014.

Ersen, A., Abdo, A., & Sahin, M.; “Temperature elevation profile inside the rat brain induced by a laser beam”; J Biomed Opt., 19(1):15009, 2014.

Seth-Vollenweider, T., Joshi, S., Dhawan, P., Sif, S. and Christakos, S. Novel mechanism of  negative regulation of 1,25-dihydroxyvitamin D3-induced 25-hydroxyvitamin D3 24-hydroxylase (Cyp24a1) transcription: epigenetic modification involving cross-talk between protein arginine methyltransferase 5 and the SWI/SNF complex.  J. Biol. Chem.  289: 33958-33970, 2014.

Paglia, D.N., Wey, A., Hreha, J., Park, A.G., Cunningham, C., Uko, L., Benevenia, J., O'Connor, J.P., & Lin, S.S.; “Local vanadium release from a calcium sulfate carrier accelerates fracture healing”; J Orthop Res., 32(5):727-34, 2014.

Saleh, S., Adamovich, S. V., & Tunik, E.; “Mirrored feedback in chronic stroke: recruitment and effective connectivity of ipsilesional sensorimotor networks”; Neurorehabil Neural Repair, 28:344-54, 2014.

Shrirao, A.B., Kung, F., Yip, D., Cho, C.H., & Townes-Anderson, E.; “Vacuum-assisted fluid flow in microchannels to pattern substrates and cells”; Biofabrication, 6(3):035016, 2014.

Wey, A., Cunningham, C., Hreha, J., Brietbart, E.A., Cottrell, J., Ippolito, J., Clark, D., Lin, H.N., Benevenia, J., O'Connor, J.P., Lin, S.S., & Paglia, D.N.; “Local ZnCl2 accelerates fracture healing”; J Orthop Res., 32(6):834-41, 2014.

O'Connor, J.P., Manigrasso, M.B., Kim, B.D., & Subramanian, S.; “Fracture healing and lipid mediators”; Bonekey Rep., 3:517, 2014.

Pilkar, R., Yarossi, M., & Nolan, K.J.; “EMG of the tibialis anterior demonstrates a training effect after utilization of a foot drop stimulator”; NeuroRehabilitation, 35(2):299-305, 2014.

Douard, V., Patel, C., Lee, J., Tharabenjasin, P., Williams, E.A., Fritton, J.C., Sabbagh, Y., & Ferraris, R.P.; “Chronic high-fructose intake reduces serum 1,25 (OH)2D3 levels in calcium-sufficient rodents”; PloS One, 9(4):e93611, 2014.

Chen, P., Goedert, K.M., Shah, P.P., Foundas, A.L., & Barrett, A.M.; “Integrity of medial temporal structures may predict better improvement of spatial neglect with prism adaptation treatment”; Brain Imaging Behav., 8(3):346-58, 2014.

Patel V, Oh A, Voit A, Sultatos LG, Babu GJ, Wilson BA, Ho M, McArdle JJ. Altered active zones, vesicle pools, nerve terminal conductivity, and morphology during experimental MuSK myasthenia gravis. PLoS One. 2014 Dec 1;9(12):e110571. doi: 10.1371/journal.pone.0110571.

Catuzzi JE, Beck KD. Anxiety vulnerability in women: a two-hit hypothesis. Exp Neurol. 2014 Sep;259:75-80. doi: 10.1016/j.expneurol.2014.01.023. Epub 2014 Feb 8.

Holloway, J. L., Allen, M. T., Myers, C. E., Servatius, R. J. (2014). Behaviorally inhibited individuals demonstrate significantly enhanced conditioned response acquisition under non-optimal learning conditions. Behavioural Brain Research, 261:49-55. PMID: 24275381. doi: 10.1016/j.bbr.2013.10.041

Heiman A, Pallottie A, Heary RF, Elkabes S.Toll-like receptors in central nervous system injury and disease: a focus on the spinal cord. Brain Behav Immun. 2014 Nov;42:232-45. doi: 10.1016/j.bbi.2014.06.203. Epub 2014 Jul 22. PMID: 25063708

Shirokova N, Kang C, Fernandez-Tenorio M, Wang W, Wang Q, Wehrens XH, Niggli E. Oxidative stress and Ca2+ release events in mouse cardiomyocytes. Biophys J. 2014 Dec 16;107(12):2815-27. doi: 10.1016/j.bpj.2014.10.054.


2013

Kyrychenko S, Poláková E, Kang C, Pocsai K, Ullrich ND, Niggli E, Shirokova N. Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy. Cardiovasc Res. 2013 Mar 15;97(4):666-75. doi: 10.1093/cvr/cvs425. Epub 2012 Dec 21. PMID: 23263329

Wood TL, Bercury KK, Cifelli SE, Mursch LE, Min J, Dai J, Macklin WB. mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development. ASN Neuro. 2013 Mar 19;5(1):e00108. doi: 10.1042/AN20120092.

Lukacs, V., Rives, J.M., Sun, X., Zakharian, E., Rohacs, T. Promiscuous activation of transient receptor potential vanilloid 1 channels by negatively charged intracellular lipids, the key role of endogenous phosphoinositides in maintaining channel activity, J. Biol. Chem. 2013 288(49):35003-13.

Cao C, Yudin Y, Bikard Y, Chen W, Liu T, Li H, Jendrossek D, Cohen A, Pavlov E, Rohacs T, Zakharian E. Polyester Modification of the Mammalian TRPM8 Channel Protein: Implications for Structure and Function. Cell Reports 2013 4(2):302-15

Lukacs V, Yudin Y, Hammond GR, Sharma E, Fukami K, Rohacs T.; Distinctive Changes in Plasma Membrane Phosphoinositides Underlie Differential Regulation of TRPV1 in Nociceptive Neurons. J Neurosci. 2013 33(28):11451-63

Cao C, Zakharian E, Borbiro I, Rohacs T. Interplay between calmodulin and phosphatidylinositol 4,5-bisphosphate in Ca2+-induced inactivation of transient receptor potential vanilloid 6 channels. J Biol Chem. 2013; 288(8):5278-90.

Nguyen KQ, Tsou WI, Kotenko S, Birge RB. 2013. TAM receptors in apoptotic cell clearance, autoimmunity, and cancer. Autoimmunity. 2013 Aug;46(5):294-7. doi: 10.3109/08916934.2013.794515. Epub 2013 May 10. Review.

Dorsey-Oresto, A., Lu, T., Mosel, M., Wang, X., Salz, T., Drlica, K., and Zhao, X.  2013.  YihE kinase is a central regulator of programmed cell death in bacteria.  Cell Reports 3: 528-537.

Mosel, M., Li, L., Drlica, K., and Zhao, X. 2013. Superoxide-mediated protection of Escherichia coli from antimicrobials.  Antimicrob. Agents Chemother. 57: 5755-5759.

Srivastava D, Hsieh ML, Khataokar A, Neiditch MB, Waters CM. Cyclic di-GMP inhibits Vibrio cholerae motility by repressing induction of transcription and inducing extracellular polysaccharide production. Mol. Microbiol. 2013 Dec; 90(6):1262-76.

Pasternack JB, Howell RW. 2013. RadNuc: a graphical user interface to deliver dose rate patterns encountered in nuclear medicine with a 137Cs irradiator. Nucl Med Biol. 2013;40:304-311.

Lu, B., J. Lee, X. Nie, M. Li1, Y.I.  Morozov, S. Venkatesh, D.F. Bogenhagen, D. Temiakov and C.K. Suzuki.  Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease.  Molecular Cell 49:121-132 (2013).

Tharabenjasin P, Douard V, Patel C, Krishnamra N, Johnson RJ, Zuo J, Ferraris RP. Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G1-12. doi: 10.1152/ajpgi.00263.2013. Acute interactions between intestinal sugar and calcium transport in vitro. Epub 2013 Oct 31.PMID: 24177030

Douard V, Sabbagh Y, Lee J, Patel C, Kemp FW, Bogden JD, Lin S, Ferraris RP. Excessive fructose intake causes 1,25-(OH)(2)D(3)-dependent inhibition of intestinal and renal calcium transport in growing rats. Am J Physiol Endocrinol Metab. 2013 Jun 15;304(12):E1303-13. doi: 10.1152/ajpendo.00582.2012. Epub 2013 Apr 9.

Gil-Mast S, Kortagere S, Kota K, Kuzhikandathil EV. An amino acid residue in the second extracellular loop determines the agonist-dependent tolerance property of the human D3 dopamine receptor. ACS Chem Neurosci. 2013 Jun 19;4(6):940-51. doi: 10.1021/cn3002202. Epub 2013 Mar 21. PMID: 23477444

M.A. Lea, M.S. Qureshi, M. Buxhoeveden, N. Gengel, J. Kleinschmit and C. desBordes. 2013. Regulation of the proliferation of colon cancer cells by compounds that affect glycolysis, including 3-bromopyruvate, 2-deoxyglucose and biguanides. Anticancer Res., 33, 401-407.

Vazirani, R.P., Fioramonti, X. and V.H. Routh. Membrane potential dye imaging of ventromedial hypothalamus neurons from adult mice to study glucose sensing. JoVE J. Vis. Exp (81) e50861, doi 10.3791/50861, 2013.

Fioramonti X., Deak, A., Deshpande, S., Carneiro, L., Zhou, C., Sayed, N., Orban, B., Berlin, J.R., Penicaud, L., Leloup, C., Beuve, A. and V. H. Routh. Hypothalamic S-Nitrosylation Contributes to the Counter-Regulatory Response Impairment Following Recurrent Hypoglycemia. PloS ONE 8(7):e68709, 2013.

Proddutur, A., Elgammal, F.S., & Santhakumar, V.; “Seizure-induced alterations in fast-spiking basket cell GABA currents modulate frequency and coherence of gamma oscillation in network simulations”; Chaos, 23(4):046109, 2013.

Kim, E.H., & Alvarez, T.L.; “Analysis of saccades and peak velocity to symmetrical convergence stimuli: binocularly normal controls compared to convergence insufficiency patients”; Invest Ophthalmol Vis Sci., 54(6):4122-35, 2013.

Kim, E.H., & Alvarez, T.L.; “The horizontal dark oculomotor rest position”; Graefes Arch Clin Exp Ophthalmol., 251(9):2119-30, 2013.

Ordek, G., Groth, J.D., & Sahin, M.; “Differential effects of ketamine/xylazine anesthesia on the cerebral and cerebellar cortical activities in the rat”; J Neurophysiol., 109(5):1435-43, 2013.

Khariv V, Pang K, Servatius RJ, David BT, Goodus MT, Beck KD, Heary RF, Elkabes S. Toll-like receptor 9 deficiency impacts sensory and motor behaviors. Brain Behav Immun. 2013 Aug;32:164-72. doi: 10.1016/j.bbi.2013.04.007. Epub 2013 Apr 24.

Shamanna RA, Hoque M, Pe'ery T, Mathews MB. 2013. Induction of p53, p21 and apoptosis by silencing the NF90/NF45 complex in human papilloma virus-transformed cervical carcinoma cells. Oncogene. 2013 Oct 24;32(43):5176-85. doi: 10.1038/onc.2012.533. Epub 2012 Dec 3. PMID:23208500

Hussain, A., Collins, G., Yip, D., & Cho, C.H.; “Functional 3-D cardiac co-culture model using bioactive chitosan nanofiber scaffolds. Biotechnol Bioeng., 110(2):637-47, 2013.

Yip, D., & Cho, C.H.; “A multicellular 3D heterospheroid model of liver tumor and stromal cells in collagen gel for anti-cancer drug testing’; Biochem Biophys Res Commun., 433(3):327-32, 2013.

Paglia, D.N., Wey, A., Brietbart, E.A, Faiwiszewski, J., Mehta, S.K., Al-Zube, L., Vaidya, S., Cottrell, J.A., Graves, D., Benevenia, J., O'Connor, J.P., & Lin, S.S.; “Effects of local insulin delivery on subperiosteal angiogenesis and mineralized tissue formation during fracture healing”; J Orthop Res., 31(5):783-91, 2013.

Skop N.B., Calderon, F., Levison, S.W., Gandhi, C.D., & Cho, C.H.; “Heparin crosslinked chitosan microspheres for the delivery of neural stem cells and growth factors for central nervous system repair”; Acta Biomater., 9(6):6834-43, 2013.

Sheynin, J., Shikari, S., Gluck, M.A., Moustafa, A.A., Servatius, R.J. & Myers, C.E.; “Enhanced avoidance learning in behaviorally inhibited young men and women”; Stress, 16(3):289-99, 2013.

Hoque M*, Ji Z*, Zheng D, Luo W, Li W, You B, Park JY, Yehia G, Tian B. (2013). Analysis of alternative cleavage and polyadenylation by 3’ region extraction and deep sequencing. Nat Methods. 10:133-9.

Matsushima S, Kuroda J, Ago T, Zhai P, Park JY, Xie LH, Tian B, Sadoshima J. (2013). Increased Oxidative Stress in the Nucleus Caused by Nox4 Mediates Oxidation of HDAC4 and Cardiac Hypertrophy. Circ Res. 112:651-63.

Devany E, Zhang X, Park JY, Tian B, Kleiman FE. (2013). Positive and negative feedback loops in the p53 and mRNA 3' processing pathways. Proc Natl Acad Sci USA. 110:3351-6.

Luo W*, Ji Z*, Pan Z*, You B, Hoque M, Li W, Gunderson SI, Tian B. (2013). The Conserved Intronic Cleavage and Polyadenylation Site of CstF-77 Gene Imparts Control of 3’ End Processing Activity through Feedback Autoregulation and by U1 snRNP. PLoS Genet. 9:e1003613. 

Cheng Y, Tian B, Miura MM. (2013). Mathematical modeling of alternative polyadenylation in the human gene, CSTF3. SIAM J Appl Math. 73:1793–1810.

Myers, C.E., Moustafa, A.A., Sheynin, J., Vanmeenen ,K.M., Gilbertson, M.W., Orr, S.P., Beck, K.D., Pang, K.C., & Servatius, R.J.; “Learning to obtain reward, but not avoid punishment, is affected by presence of PTSD symptoms in male veterans: empirical data and computational model”; PLoS One, 8(8):e72508, 2013.

Sehgel, N.L., Zhu, Y., Sun, Z., Trzeciakowski, J.P., Hong, Z., Hunter, W.C., Vatner, D.E., Meininger, G.A. & Vatner, S.F.; “Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension.”; Am J Physiol Heart Circ Physiol., 305(9):H1281-7, 2013.

Damcott, M., Blochlinger, S., & Foulds, R.A.; “Effects of passive versus dynamic loading interventions on bone health in children who are nonambulatory”; Pediatr Phys Ther., 25(3):248-55, 2013.

Damaraju, S.M., Wu, S., Jaffe, M., & Arinzeh, T.L. “Structural changes in PVDF fibers due to electrospinning and its effect on biological function”; Biomed Mater., 8(4):045007, 2013.

Guo, Y., Sahin, M., Foulds, R.A., & Adamovich, S.V.; “Corticospinal signals recorded with MEAs can predict the volitional forearm forces in rats”; Conf Proc IEEE Eng Med Biol Soc., 2013:1984-7, 2013.

Abdo, A., Ersen, A., & Sahin, M.; “Near-infrared light penetration profile in the rodent brain.”; J Biomed Opt., 18(7):075001, 2013.

Yu,  J., Proddutur, A., Elgammal, F.S., Ito, T., & Santhakumar, V.; “Status epilepticus enhances tonic GABA currents and depolarizes GABA reversal potential in dentate fast-spiking basket cells”; J Neurophysiol., 109(7):1746-63, 2013.

Park, A.G., Paglia, D.N., Al-Zube, L., Hreha, J., Vaidya, S., Brietbart, E.A., Benevenia, J., O'Connor, J.P., & Lin, S.S.; “Local insulin therapy affects fracture healing in a rat model”; J Orthop Res., 31(5):776-82, 2013.

Nolan, K.J., Yarossi, M., & Ramanujam, A.; “Measuring ambulation in adults with central neurologic disorders”; Phys Med Rehabil Clin N Am., 24(2):247-63, 2013.

Tunik, E., Saleh, S., & Adamovich, S. V.; “Visuomotor discordance during visually-guided hand movement in virtual reality modulates sensorimotor cortical activity in healthy and hemiparetic subjects”; J Neurophysiol., 21: 198-207, 2013.

Bagce, H. F., Saleh, S., Adamovich, S. V., Krakauer, J. W., & Tunik, E.; “Corticospinal excitability is enhanced after visuomotor adaptation and depends on learning rather than performance or error”; IEEE Trans Neural Syst Rehabil Eng., 109:1097-106, 2013.

Jebiwott S., Govindaswamy K., Mbugua A. and Bhanot P. (2013) Plasmodium berghei Calcium Dependent Protein Kinase 1 is not required for host cell invasion. PLoS One  8(11): e79171. PMID: 24265753


2012

Chen-Deutsch X, Kutner A, Harrison JS, Studzinski GP. 2012. The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells. Leuk Res. 2012 Jul;36(7):884-8. doi: 10.1016/j.leukres.2012.03.023. Epub 2012 Apr 26.

Chen-Deutsch X, Studzinski GP. 2012. Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1α,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistance. Cell Cycle. 2012 Apr 1;11(7):1364-73. doi: 10.4161/cc.19765. Epub 2012 Apr 1.

Panchal D., Govindasamy K., Rana, A. and Bhanot P. (2012).  Improved Plasmodium berghei lines for conditional mutagenesis. Molecular and Biochemical Parasitology 184(1): 52-4. PMID: 22450301

Duggal J, Harrison JS, Studzinski GP, Wang X. 2012. Involvement of microRNA181a in differentiation and cell cycle arrest induced by a plant-derived antioxidant carnosic acid and vitamin D analog doxercalciferol in human leukemia cells. Microrna. 2012;1(1):26-33

Yuan Y, Kasar S, Underbayev C, Vollenweider D, Salerno E, Kotenko SV, Raveche E. 2012. Role of microRNA-15a in autoantibody production in interferon-augmented murine model of lupus.Mol Immunol. 2012 Sep;52(2):61-70. doi:10.1016/j.molimm.2012.04.007. Epub 2012 May 11

Guito, J and DM Lukac (2012). KSHV Rta Promoter Specification and Viral Reactivation. Front. Microbiol. 3:30.

Paglia, D.N., Wey, A., Park, A.G., Brietbart, E.A, , Mehta, S.K., Bogden, J.D., Kemp, F.W., Benevenia, J., O'Connor, J.P., & Lin, S.S.; “The effects of local vanadium treatment on angiogenesis and chondrogenesis during fracture healing”; J Orthop Res., 30(12):1971-8, 2012.

Ordek, G., Groth, J.D., & Sahin, M.; “Effect of anesthesia on spontaneous activity and evoked potentials of the cerebellar cortex”; Conf Proc IEEE Eng Med Biol Soc., 2012:835-8, 2012.

Rohafza, M., Fluet, G.G., Qiu, Q., & Adamovich, S.V.; ”Correlations between statistical models of robotically collected kinematics and clinical measures of upper extremity function”; Conf Proc IEEE Eng Med Biol Soc., 2012:4120-3, 2012.

Fluet, G.G., Merians, A.S., Qiu, Q., Lafond, I., Saleh, S., Ruano, V., Delmonico, A.R., & Adamovich, S.V.; Robots integrated with virtual reality simulations for customized motor training in a person with upper extremity hemiparesis: a case study. J Neurol Phys Ther., 36(2):79-86, 2012.

Chitravanshi, V.C., Proddutur, A., & Sapru, H.N.; “Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II”; Exp Physiol., 97(9):1001-17, 2012.

Pilkar, R., Yarossi, M., & Forrest, G.; “Empirical mode decomposition as a tool to remove the function electrical stimulation artifact from surface electromyograms: preliminary investigation”; Conf Proc IEEE Eng Med Biol Soc., 2012:1847-50, 2012.

Shrirao, A.B., Hussain, A., Cho, C.H., & Perez-Castillejos, R.; ” Adhesive-tape soft lithography for patterning mammalian cells: application to wound-healing assays. Biotechniques, 53(5):315-18, 2012.

Alvarez, T.L., Kim, E.H., Vicci VR, Dhar SK, Biswal, B.B., & Barrett, A.M.; “Concurrent vision dysfunctions in convergence insufficiency with traumatic brain injury; Optom Vis Sci., 89(12):1740-51, 2012.

Kim, E.H., & Alvarez, T.L.; “The changes in phoria and convergence to divergence peak velocity ratio are correlated”; Curr Eye Res., 37(11):1054-65, 2012.

Kim, E.H., & Alvarez, T.L.; “The frequency of horizontal saccades in near and far symmetrical disparity vergence”; Vision Res., 15;63:9-19, 2012.

Shah, P.P., Gonzalez, K.O., & Barrett, A.M.; “Line copying: distinct "where" and "aiming" spatial bias in healthy adults”; Cogn Behav Neurol., 25(2):77-84, 2012.

Saleh, S., Adamovich, S. V., & Tunik, E.; “Resting state functional connectivity and task-related effective connectivity changes after upper extremity rehabilitation: a pilot study”; Conf Proc IEEE Eng Med Biol Soc., 2012:4559-62, 2012.

Bagce, H. F., Saleh, S., Adamovich, S. V., & Tunik, E.; “Visuomotor gain distortion alters online motor performance and enhances primary motor cortex excitability in patients with stroke”; Neuromodulation, 15:361-6, 2012.

Li W, Laishram RS, Ji Z, Barlow CA, Tian B, Anderson RA. (2012). Star-PAP Control of BIK Expression and Apoptosis is Regulated by Nuclear PIPKIα and PKCδ Signaling. Mol Cell. 45:25-37.

Zhao X, Park JY, Ho D, Gao S, Yan L, Ge H, Ilsmaa S, Lin L, Tian B, Vatner D, Graham R, Vatner S. (2012). Cardiomyocyte Overexpression of the α1A-Adrenergic Receptor in the Rat Phenocopies Second But Not First Window Preconditioning. Am J Physiol Heart Circ Physiol. 302:H1614-24.

Oka SI, Zhai P, Alcendor R, Park JY, Tian B, Sadoshima J. (2012). Suppression of ERR targets by a PPARα/Sirt1 complex in the failing heart. Cell Cycle. 11:856-64.

Haenni S*, Ji Z*, Hoque M, Rust N, Sharpe H, Eberhard R, Browne C, Hengartner MO, Mellor J, Tian B, Furger A. (2012). Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3'-end-seq. Nucleic Acids Res. 40:6304-18.

Xie LH, Shanmugam M, Park JY, Zhao Z, Wen H, Tian B, Periasamy M, Babu GJ. (2012). Ablation of sarcolipin results in atrial remodeling. Am J Physiol Cell Physiol. 302:C1762-71.

Neff AT, Lee JY, Wilusz J, Tian B, Wilusz CJ. (2012). Global analysis reveals multiple pathways for unique regulation of mRNA decay in induced pluripotent stem cells. Genome Res. 22:1457-67.

Lee JE, Lee JY, Trembly J, Wilusz J, Tian B, Wilusz CJ. (2012). The PARN deadenylase targets a discrete set of mRNAs for decay and regulates cell motility in mouse myoblasts. PLoS Genet. 8: e1002901.

Henriques T, Ji Z, Tan-Wong SM, Carmo AM, Tian B, Proudfoot NJ, Moreira A. (2012). Transcription termination between polo and snap, two closely spaced tandem genes of D. melanogaster. Transcription. 3:198-212.

Yan L, Park JY, Dillinger JG, De Lorenzo MS, Yuan C, Lai L, Wang C, Ho D, Tian B, Stanley WC, Auwerx J, Vatner DE, Vatner SF. (2012). Common Mechanisms for Calorie Restriction and AC5 Knockout Models of Longevity. Aging Cell. 11:1110-20.

Li W*, Yeh HJ*, Shankarling GS, Ji Z, Tian B, Macdonald CC. (2012). The τCstF-64 Polyadenylation Protein Controls Genome Expression in Testis. PLoS ONE. 7:e48373.

Bravo C, Kudej RK, Yuan C, Yoon S, Ge H, Park JY, Tian B, Stanley WC, Vatner SF, Vatner DE, Yan L. (2012). Metabolomic Analysis of Two Different Models of Delayed Preconditioning. J Mol Cell Cardiol. 55:19-26.

Christakos, S., Ajibade, D. V., Dhawan, P., Fechner, A. J. and Mady, L. J. Vitamin D metabolism. Rheum. Dis. Clin. North Am. 38: 1-11, 2012.

Crassous PA1, Couloubaly S, Huang C, Zhou Z, Baskaran P, Kim DD, Papapetropoulos A, Fioramonti X, Durán WN, Beuve A. Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model. Am J Physiol Heart Circ Physiol. 2012 Sep 1;303(5):H597-604. doi: 10.1152/ajpheart.00138.2012. Epub 2012 Jun 22.

Sundararajan, V., Lee, J., Singh, K., Lee I., and Suzuki, C.K. Multitasking in the mitochondrion by the ATP-dependent Lon protease.  Biochim. Biophys. Acta.  Invited review on AAA+ proteins. 1823(1):56 (2012).

Bernstein, S.H., Venkatesh, S. Li, M., Lee, J., Lu B., Hilchey, S.P., Morse, K.M., Metcalf, H.M., Andreeff, M., Brookes, P.S. and Suzuki, C.K., The mitochondrial ATP-dependent Lon protease: a novel drug target in lymphoma death mediated by the synthetic triterpenoids CDDO and its derivatives.  Blood 119:3321 (2012).

Malik, M., Chavda, K.,  Zhao, X., Shah, N., Hussain, S., Kurepina, N., Kreiswirth, B., Kerns, R.J., and Drlica, K. 2012. Induction of mycobacterial resistance to quinolone class antimicrobials.  Antimicrobial Agents Chemother. 56: 3879-3887.

Holloway, J.L, Trivedi, P., Myers, C.E. & Servatius, R.J. (2012). Enhanced contitioned eyeblink response acuisition and proactive interference in anxiety vulnerable individuals. Frontiers in Behavioural Neuroscience, 6:76. PMID: 23162449; PMCID: PMC349907.