Cardiovascular Biology

The Cell Biology, Neuroscience and Physiology (CBNP) doctoral track offers specialized training and research opportunities in cardiovascular biology. CNBP faculty research interests include regulation of gene expression, transcriptome, DNA repair, mitochondrial quality control, autophagy, cell cycle, and signal transduction pathways in normal and diseased tissue, with particular emphasis on the molecular mechanisms of heart and vascular disease, muscular dystrophy, cardiovascular control, cancer, angiogenesis, the application of induced pluripotent stem cells for regenerative medicine, and translational research. Approaches include animal models of cardiac disease, cutting-edge technologies in cell biology, molecular biology, molecular genetics, genomics, and proteomics, and advanced histological and cell/tissue culture methods. Exceptional laboratory and animal facilities, equipment, and computational services, as well as state-of-the-art core research facilities providing transgenic, molecular, genomic, proteomic, microscopic, flow cytometry, and biostatistics/bioinformatics support are available, as are school-wide services for mouse physiology, human induced pluripotent stem cells, and adeno-associated viral vectors. This rich doctoral training environment provides an ideal setting to explore cardiovascular regulation and disease processes.

Our Faculty:

Faculty are drawn from several Departments including Cell Biology and Molecular Medicine, Microbiology, Biochemistry and Molecular Genetics, Pharmacology, Physiology and Neuroscience

Courses:

Students need to take the two core courses to fulfill the subdiscipline requirements, for a total of 6 credits. The students are also encouraged to take the elective course.

Core courses:

• Molecular Medicine of the Heart (CBMM 5350Q), 3 credits
• Molecular Mechanism of disease (CBNP 5068Q), 3 credits

Elective:

• Foundations of Integrative Human Physiology (CBNP 5165Q), 2 credits