Certificate in Neuroscience
Rutgers School of Graduate Studies, Newark Health Science Campus
1. Goals:
To provide graduate students with a comprehensive introduction to the  Neurosciences that encompasses both basic science and clinical aspects.
2.   Intended Applicant Pool:
        Health  professionals or future health professionals who are interested in learning  more about the functions and dysfunctions of the nervous system.
        Individuals interested in the pharmaceutical  biotech industries.
        Employees in health related research fields who  want to gain expertise in neuroscience  
  
  3. Competencies of Certificate Graduates:
        Students will be able to: 
        Understand  the essential properties of neural cells as they relate to their functions.
        Understand  the anatomy of the nervous system and how each division alone and in  conjunction with other divisions coordinates neural functions.
        Understand  how to apply the research tools of modern biomedical science to neuroscience.
  Acquire the  knowledge required to understand the molecular and cellular bases for  neurological and psychiatric diseases and their treatment.
4. Curriculum:  
There are 4 required courses and some electives to earn 18  credits for the Certificate.
Required courses are:
A. GSND N500AQ Fundamentals of Biomedical Sciences A. Biochemistry and  Molecular Biology. 3 cr. Fall (Evening course)
This course is Part I of the evening fundamentals course that is given to  Masters Students. This course covers basic biochemistry and molecular biology.  The nature of the major macromolecules will be discussed and their role in  the regulation of carbohydrate, lipid and amino acid metabolism will be  illustrated. The synthesis of proteins and nucleic acids will be reviewed and  the experimental techniques used in molecular biology will be considered.  A review of the regulation of gene expression and intermediary metabolism will  serve as an introduction to a more extensive consideration of the material to  be discussed in the cell biology course in the following semester.  Throughout the course an effort will be made to indicate the relevance of  biochemistry to clinical medicine.
B. GSND N500BQ Fundamentals of Biomedical Sciences II. Cellular Biology. 3  cr. Spring  (Evening course)
This course is Part II of the evening fundamentals course that is given to  Masters Students. In this course students are introduced to basic cellular  structure and function. Topics include: an introduction to the  techniques used for studying cell biology, biomembranes, cell  compartments, exocytosis and endocytosis, the nucleus, cell cycle and  apoptosis, cell signaling, cytoskeleton, extracellular matrix, angiogenesis,  wound repair, cell surface specializations and junctions, and basic tissue  biology of epithelia, connective tissue and nerve tissue. The lecture series  provides an overview of important concepts in cell biology. Key experiments  are described and some of the relevant topics of cell biology in the news  are discussed. 
C. Fundamentals of Neuroscience (NEUR 5200Q) 3 cr. Fall  
        This course introduces students to the  gross and microscopic anatomy of the nervous system with an emphasis upon the  functions of each of the major subdivisions of the brain and spinal cord as  well as the functions of each of the major cell types that comprise the CNS and  PNS.  Students also will be provided information on the biochemistry and  physiology of the nervous system. The student will gain an overall view of the  field of neuroscience, experience in reading the literature and in presenting  neuroscience topics to an audience. 
D. Neurobiology of Disease (NEUR N5040), 3  cr. Spring 
        The goal of this course is to provide an overview of the neurobiological basis  of selected medical disorders. This course will focus on the molecular,  cellular and behavioral mechanisms underlying neurological and psychiatric  disorders including epilepsy, Multiple Sclerosis, Parkinson's, Alzheimer's,  Depression, Schizophrenia, Addiction, Autism, CNS infections, brain and spinal  cord injury and stroke. Lectures will include an overview of neural systems  implicated in the diseases, the major issues that are being addressed in basic  research in order to elucidate the molecular and cellular mechanisms underlying  neural dysfunction and the approaches used to treat disease symptoms. Classes  will consist of lectures by the instructors and student presentations on topics  related to the lecture themes. Prerequisite: Fundamentals  of Neuroscience.
Students may choose any one of the following electives:
Behavioral &  Cognitive Neuroscience (CBNP 5032Q) 2 cr.  Fall
        This  course focuses on the underlying neurobiological and neurophysiological  processes that are responsible for the expression of behavior and cognitive  processes. This course is team-taught and covers a range of topics including:
        Human  Cognitive Development, Attention & Perception, Motivation & Higher Processes,  Sleep & Rhythms, Learning and Memory, Aging & Amnesia and 
        Spatial  Cognition.  
       Prerequisite: Fundamentals of  Neuroscience or another introductory neuroscience course. 
Cellular and  Developmental Neuroscience (CBNP 5150Q), 2 Cr. Fall
        Cellular  and Developmental Neuroscience provides more detailed understanding of the  cells that comprise the nervous system and how they arise during development. The  course begins with an overview of the structure of the Central Nervous System.  The first half of the course then analyzes the functions of the cells that  comprise this complicated organ. The second half of the course focusses on how  these cells are generated during development, how the different regions of the  brain are patterned, how developing neurons form appropriate connections and  the factors that contribute to their ultimate survival and differentiation.
          Prerequisite: Fundamentals  of Neuroscience or another introductory neuroscience course. 
Neuroendocrinology:  Regulation of Physiological Processes (PHPY 5085Q), 2 Cr. Spring 
        This course is offered  through the Pharmacology & Physiology department. The focus of the course  will be on the neuroendocrine regulation of physiological processes with an  emphasis on metabolism. The format will be a mixture of didactic lectures and  student presentations. The class will meet twice weekly for 2 hours for 7  weeks.  The first session of each week will use lectures to introduce a  topic or neuroendocrine system. During the second session a student will lead a  discussion of a current topic in the field covered earlier that week based  around a presentation of a journal article. The instructor will provide a list  of articles from which the students can choose. The final session will be an  exam representing 30% of the grade. Presentations and class participation make  up the remainder of the grade.
            Prerequisite: Core course (either Masters or PhD program) required.  Physiological Principles and/or Fundamentals of Neuroscience suggested.  Exceptions made (frequently) at the discretion of the instructor. 
Systems Neuroscience (CBNP  5033Q) 2 Cr. Spring
        This Systems Neuroscience  course will cover the organization and function of sensory, motor, and  endocrine systems, and central control of autonomic and cardiovascular  systems.  By the end of the course,  students should have a fundamental knowledge of the anatomy, biochemistry,  physiology and function of each of the systems. 
      Prerequisite: Fundamentals of Neuroscience or another introductory neuroscience course. 
Topics in Neuroimmunology  (CBNP 5140Q), 2 Cr. Spring 
        This course provides an  overview of the bidirectional interaction between the central nervous system  and the immune system.  This interaction is discussed in terms of  innervations of lymphoid organs, effect of neurotransmitters on immune system,  neuroendocrine pathways, expression and function of innate and adaptive immune  system mediators in the nervous system and the immunological mechanisms  underlying neurological diseases including multiple sclerosis, myasthenia  gravis, autism, epilepsy and others. 
Neuroscience courses not  listed above may be credited towards a Neuroscience Concentration upon review  and approval of the neuroscience program coordinator.
        5.  Program Coordinator:
        Steven W. Levison, PhD
        Professor of Neuroscience
        Director, Laboratory for Regenerative Neurobiology
        Department of Pharmacology, Physiology and Neuroscience
        NJMS Cancer Research Center
        Office H-1226
        205 South Orange Ave
        Newark, NJ 07103
        PH (973) 972-5162
        Fax (973) 972-2668
        Email: steve.levison@rutgers.edu
