Neuropathic Pain Research

Neuropathic pain is a debilitating condition associated with different pathologies including chronic spinal cord injury, multiple sclerosis, and peripheral nerve injury. Despite advances, the mechanisms underlying neuropathic pain are not well understood and currently available pharmacotherapies do not adequately alleviate neuropathic pain and have serious adverse effects. The goal of neuropathic pain research in the department is to discover novel therapeutic targets and develop new approaches for the effective alleviation of pain.
The investigations focus on molecular mechanisms underlying neuropathic pain in the dorsal horn in animal models of spinal cord injury and multiple sclerosis with particular emphasis on the role of neuronal calcium pumps and innate immune receptors.

Stella Elkabes, Ph.D.

Professor

Department of Neurosurgery