The main focus of the Department of Orthopaedics is on the mechano-biology of bone healing.
There are two key research areas:
1. Biomechanics of joints and bone fixation devices
2. In vivo and in vitro biology and mechanics of bone remodeling
The biomechanics lab is employing custom-made jigs to test performance and endurance of orthopaedic devices, such as endoprostheses and external fixators, by replicating in vivo loading conditions on bone-implant compounds. Novel implants, in combination with osteogenic drugs, are routinely tested.
The bone biology labs use molecular genetics, bioengineering and bioimaging techniques to study the effectors that control cell lineage choice and osteoblast differentiation from mesenchymal stem cells. Standard systems include cell culture and in vivo models.