This was developed by Alexander G. Izaguirre & Dr. Anthony Grygotis
Slides 28
[Lab 6] [Slides 73] [Slides 25] [Slides 66] [Slides 28] [Slides 16] [Slides 57] [Slides 91] [Slides 43] [Slides 23]

28.PROSTATE: ADENOCARCINOMA

PERTINENT CHANGES:

     
  1. The normal architecture of the gland is almost completely disrupted by the presence of epithelial tumor cells arranged singly, in cords and in glands.
  2. These cells vary only slightly in size and shape.
  3. The nuclei are oval, round or polygonal in shape.
  4. Most nuclei are dark staining.
  5. Tumor cells infiltrate the stroma.

28A.  Gross specimen of prostate and lower bladder with probe in urethra.  Prostate is largely replaced by yellow white tumor that extends into the floor of the bladder, seen as rounded projections in trigone

28B.  Low power.  Tumor cells with dark staining nuclei in small, irregular glands, small nests, or individual cells infiltrate the stroma in a haphazard fashion

28C.  Medium power, similar to image 20B and showing glands to be lined by a single layer of  cells with hyperchromatic nuclei

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[Lab 6] [Slides 73] [Slides 25] [Slides 66] [Slides 28] [Slides 16] [Slides 57] [Slides 91] [Slides 43] [Slides 23]

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