Supplement
[Lab 3] [Slides 70] [Slides 51] [Supplement] [Slide 41] [Slides 40] [Slides 69] [Slides 87]

Lipoid Nephrosis

F.  High power.  Light microscopy shows no morphologic changes.

Focal Segmental Glomerulosclerosis

H.  Medium power shows two glomeruli with partial ("segmental") sclerosis or hyalinization.  Not all glomeruli are affected equally (hence "focal").

Membranoproliferative Glomerulonephritis (MPGN)

I.  High power shows both cellular proliferation and membranous thickening throughout the glomerulus.

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[Lab 3] [Slides 70] [Slides 51] [Supplement] [Slide 41] [Slides 40] [Slides 69] [Slides 87]

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G.  Electron micrograph of glomerulus.  Ultrastructural examination reveals fusion of epithelial foot processes but no other abnormalities.

J.  Jones silver stain shows "splitting" of the GBM brought about by subendothelial interposition of mesangial cells and deposition of new basement membrane material beneath the endothelium, giving rise to the "tram track" appearance.