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Graduate School of Biomedical Sciences-Newark
Certificate in Pharmacological Sciences
To obtain a Certificate in Pharmacological Sciences, all students must successfully complete a total of 18 credits. As part of those 18 credits, all students are required to take:
GSND N500AQ Fundamentals of Biomedical Sciences A. Biochemistry and Molecular Biology.
3 cr. Fall
This course is Part I of the evening fundamentals course that is given to Masters Students. This course covers basic biochemistry and molecular biology. The nature of the major macromolecules will be discussed and their role in the regulation of carbohydrate, lipid and amino acid metabolism will be illustrated. The synthesis of proteins and nucleic acids will be reviewed and the experimental techniques used in molecular biology will be considered. A review of the regulation of gene expression and intermediary metabolism will serve as an introduction to a more extensive consideration of the material to be discussed in the cell biology course in the following semester. Throughout the course an effort will be made to indicate the relevance of biochemistry to clinical medicine.
GSND N500BQ Fundamentals of Biomedical Sciences II. Cellular Biology. 3 cr. Spring
This course is Part II of the evening fundamentals course that is given to Masters Students. In this course students are introduced to basic cellular structure and function. Topics include: an introduction to the techniques used for studying cell biology, biomembranes, cell compartments, exocytosis and endocytosis, the nucleus, cell cycle and apoptosis, cell signaling, cytoskeleton, extracellular matrix, angiogenesis, wound repair, cell surface specializations and junctions, and basic tissue biology of epithelia, connective tissue and nerve tissue. The lecture series provides an overview of important concepts in cell biology. Key experiments are described and some of the relevant topics of cell biology in the news are discussed.
PHPY5021Q Fundamentals of Pharmacology. 3 cr. Fall
The course covers the fundamental concepts of dose-response relationships, pharmacokinetic models, drug-receptor interaction, absorption, distribution, biotransformation and elimination. Drug design and the drug discovery and approval process will be discussed. In addition, this course will enable students to critically evaluate new developments in the field as well as to be able to discuss controversies using general principles to evaluate the risk versus benefit ratio for the administration of drugs. The course focuses upon the principles of pharmacology and not on specific pharmacotherapeutics, although a number of drugs are used to illustrate general principles.
PHPY N5030Q Topics in Pharmacology. 3 cr. Spring
This course will cover a few selected areas in pharmacology. Drugs used in treatment of central nervous system disorders, endocrine clinical problems and chemotherapy. Textbooks: Goodman & Gilman’s “The Pharmacologic Basics of Therapeutics” and Katzung’s “Basic and Clinical Pharmacology.” Jan-May
Students choose any one of the following courses:
PHPY N5225Q Principles of Toxicology. 3 cr. Fall
This interdisciplinary course will survey the principles of toxicology that pertain to human health. Course content will include an historical background of toxicology and classroom instruction on organ and physiologic system dysfunction following exposure to toxic agents with emphasis on diagnostic techniques. Selected topics include: genotoxicity; carcinogenicity; teratology, toxicity of the central nervous; reproductive, respiratory and hematological systems; hepatic, renal, dermal and ocular toxicity. Presentation: an evidence oriented approach; material is presented through a series of lectures, small group discussions and self-study modules.
PHPY N526Q Prinicples of Toxicology II. 3 cr. Spring
PATH N5209Q The Business of Science: Drug Development - From Molecules to Medicine. 3 cr. Fall
The goals of this course are to survey the basic concepts and strategies for drug discovery and development, with an emphasis on practical applications rather than theory; provide in-depth consideration of the key phases of pre-clinical drug discovery; examine the impact of rapidly changing “disruptive technologies” on the processes of drug discovery; study the basic design and conduct of phase 1-4 clinical trials; provide a forum for discussion of practical considerations of careers in drug discovery/development; and provide and opportunity for practical application of concepts.
GSND 5215Q Animal Models of Human Disease. 3 cr. Spring
This course will provide the background, history, rationale, limitations and regulations for using animal models in biomedical research. Part of the course will be didactic lectures on topics including genetically engineered models, oncology models, pharmaceutical research, and translational models. Faculty presentations will describe existing models. Student presentations will be given on novel animal models.
Carol Lutz, PhD
Associate Professor, Department of Microbiology, Biochemistry and Molecular Genetics
Assistant Dean for Curriculum, School of Graduate Studies
Molecular Biology, Genetics and Cancer Track Director
Rutgers Biomedical and Health Sciences, New Jersey Medical School
Newark, NJ 07103