Multidisciplinary PhD Program in
Biomedical Sciences
Cell Biology, Neuroscience and Physiology (CBNP) Track
Faculty Listing |
|
Abdellatif, Maha |
Alternations of bioenergetics and genome-wide transcriptional factors in cardiac hypertrophy and heart failure. |
Ahn, Hyung Jin |
Cerebrovascular dysfunction is one of the pathological hallmarks of Alzheimer's disease (AD). Our lab is interested in the crosstalk between the cerebrovascular system and the nervous system in AD pathogenesis. |
Astrof, Sophie |
Molecular mechanisms and signaling pathways in cardiovascular development and remodeling. |
Babu, Gopal |
Research interests are studying (1) the abnormal Ca2+ handling in the pathogenesis of atrial arrhythmias and (2) the proteasome activation in cardiac pathology. |
Bartlett, Paula |
Mechanisms which elicit and maintain hormone-induced Ca2+ oscillations in the liver, and the role Ca2+ dysfunction plays in the pathogenesis of disease states such as alcoholic and non-alcoholic fatty liver disease. |
Beck, Kevin |
Stress/anxiety vulnerability, neuroendocrinology of sex differences in stress responsiveness and learning, neural basis of avoidance behavior. |
Berlin, Joshua |
P-type active ion transporters: ion transport mechanism and roles in disease processes. Cellular mechanisms underlying acute traumatic brain injury. |
Beuve, Annie |
NO-cGMP signaling with biochemistry and integrative physiology tools. This pathway is critical for synaptic plasticity and regulation of blood pressure. |
Bocarsly, Miriam |
Brain circuitry underlying naturally rewarding behaviors, such as food consumption, and how it is affected in instances of obesity. |
Boukrina, Olga |
Behavioral and physiological research to improve the understanding, diagnosis and treatment of stroke-related impairments in reading and spatial processing. |
Carcea, Ioana |
How mammals process social information, and the neuronal mechanisms by which this information impacts brain states, neuronal plasticity and behavior. |
Chitravanshi, Vineet |
Central control of cardiovascular and respiratory functions, identification of neurotransmitters in different cardiovascular and respiratory reflex mechanisms. |
Christakos, Sylvia |
The object of research in the Christakos lab is to obtain a better understanding of the molecular mechanism of action of vitamin D. |
Citron, Bruce |
Health of neurons in the CNS, dysregulation tipping the status to neurodegeneration in traumatic brain injury and Gulf War illness, and transcription factors that can be targeted to achieve neuroprotection. |
D'Adamio, Luciano |
Molecular mechanisms causing neurodegenerative disorders, characterization of new drug targets and development of lead compounds showing disease modifying activity. |
De Lorenzo, Mariana |
Effects of energy balance on aging, tumor microenvironment and progression. |
Del Re, Dominic |
Novel signaling pathways mediating heart injury following ischemic stress. HIPPO signaling in multiple cardiac cell types. |
Delic, Vedad |
Mechanisms of progressive neuronal loss in Parkinson’s disease (PD) and repetitive mild traumatic brain injuries (r-mTBI). Determining the biological link between r-mTBI and increased risk for PD. |
Diehl, Scott |
Genetic polymorphisms from arrays or next generation sequencing to reveal the causes of individual differences in disease risk and response. |
Duran, Walter |
Signaling mechanisms that regulate microvascular transport in health and disease. Signaling cascades associated with eNOS-derived nitric oxide. |
Elkabes, Stella |
The molecular and cellular mechanisms of neuronal degeneration and protection in animal models of multiple sclerosis and spinal cord injury are investigated. |
Ferraris, Ronaldo |
The role of epithelial cell differentiation in modulating sensing of nutrients and gut microbiota; intestinal responses to probiotics; oxidative stress from sugars |
Falvo, Michael |
Dyspnea, Exercise intolerance, Clinical exercise physiology, Cardiopulmonary function and assessment, Environmental and occupational exposure |
Fraidenraich, Diego |
Pluripotent stem cell based repair of cardiac and skeletal muscle defects using mouse models of human disease. |
Gaspers, Lawrence |
Role of Ca2+ signaling in regulating mitochondrial physiology and pathophysiology, and how adaptations in Ca2+ homeostasis may contribute to the onset and development of liver diseases. |
Gunal, Ozlem |
Molecular mechanisms affecting neuronal function and plasticity in rodent models of neuropsychiatric disorders, including autism, intellectual disability, and addiction behavior. |
Harris, Andrew |
Structure-function of connexin channels and the roles they play in physiology & pathology, utilizing biophysical, biochemical, genetic and cellular approaches. |
Hilfiker, Sabine |
Molecular mechanisms underlying Parkinson´s disease, determination of pathological cell biologial events and signaling cascades to uncover disease-modifying targets and strategies. |
Hu, Huijuan |
Transient Receptor Potential (TRP) channels in nociception, peripheral and central mechanisms of pain sensitization. |
Levison, Steven |
Regeneration of the CNS after pediatric stroke and traumatic injuries by understanding how to expand resident neural stem cells and coordinate a regenerative response to injury. |
Li, Hong |
Development of mass spectrometry technologies to study the role of protein post-translational modifications and protein-protein interactions in regulation. |
Lin, Sheldon |
Ortho bone regeneration medicine: focus on stem cell, growth factor and systems in several models (long bone, fracture, fusion) of normal/impaired Diabetes mellitus. |
Liu, Dongfang |
Immunobiology of NK and chimeric antigen receptor (CAR)-NK, focusing on immunological synapse, CAR immunotherapy, and HIV-specific CTLs in chronic HIV and its related malignancies |
Muresan, Virgil |
Molecular mechanisms that operate in neurodegenerative diseases, such as Alzheimer's disease and ALS, with a focus on abnormalities in axonal transport |
Myers, Catherine |
Our lab conducts research on learning and memory, and how it is disrupted following injury or disease. |
Olarerin-George, Anthony |
Discovering the function and regulation of RNA chemical modifications in the cell using biochemical, molecular and computational biology approaches. |
Pan, Ying-Xian |
Understand molecular and cellular mechanisms of mu opioid receptor actions and development of novel opioid analgesics |
Parveen, Nikhat |
Molecular basis of pathogenesis of Pseudomonas aeruginosa, Lyme disease causing Borrelia burgdorferi and syphilis causing Treponema pallidum. |
Petrou, Vasileios |
Structural studies of membrane enzymes and receptors relevant to antibiotic resistance or human physiology and pathology using single-particle cryo-electron microscopy. |
Rogers, Melissa |
Studies of transcriptional & post-transcriptional Bone Morphogenetic Protein 2 gene regulation as relevant to embryogenesis, cancer, & vascular calcification. |
Rohacs, Tibor |
Regulation of heat- and cold-activated TRP and mechanically-activated Piezo ion channels in sensory neurons, and their roles in somatosensory touch, pain and itch. |
Rohowsky-Kochan, Christine |
Mechanisms that regulate immune responses and strategies to manipulate these responses in autoimmunity and neurological diseases. |
Routh, Vanessa |
Mechanisms by which the brain senses and responds to peripheral nutrient homeostasis and associated dysfunction during obesity, diabetes and disease anorexia |
Sadoshima, Junichi |
Cardiovascular biology; signal transduction mechanisms in the cardiovascular system; stem cells. |
Saleh, Soha |
Dr. Saleh studies underlying mechanisms of neuromuscular function, specifically neural networks involved in motor learning and control, and neuroplasticity after injury and in response to rehabilitation interventions. |
Sayed, Danish |
Molecular cardiology; transcriptional and posttranscriptional mechanisms of gene regulation in cardiovascular systems. |
Serrador, Jorge |
Cerebral blood flow regulation and the role of the vestibular system in cardiovascular and cerebrovascular control. Enhancing neural systems using stochastic resonance. Sex differences in human physiology. |
Shimizu, Emi |
Molecular and physiological mechanisms regulating tertiary dentin formation, as well as pulp regeneration technology using induced pluripotent stem cells (iPSC) and oral stem cells. |
Shirokov, Roman |
To understand how ion channels sense transmembrane voltage, we analyze structure-function relationships in sodium and calcium channels. We also develop novel bioinformatics algorithms to predict effects of site-directed mutations and naturally occurring variants. |
Siracusa, Mark |
Early cellular and molecular events that promote inflammation in the context of protective immunity to helminths and allergic disease. |
Stephens, Robin |
Systemic Inflammation and the Neuro-Glial-Vascular unit. Mechanisms of neuroinflammation and sickness behavior in Cerebral Malaria including glial surveillance and neuroprotection and the roles of vascular congestion, neural hyperexcitability and seizure susceptibility in cerebral malaria pathogenesis. |
Sugimoto, Katsunori |
Cellular DNA damage response, telomere maintenance, cell senescence and transcriptional control. |
Tambini, Marc D. |
The Tambini Lab is focused on understanding the normal function of the Amyloid Precursor Protein (APP), the effect of Alzheimer's Disease-associated APP mutations on the function of APP as it relates to the content, target, and function of APP-containing extracellular vesicles. To accomplish this research goals, we use cellular and knock-in rat models of AD, combined with biochemical, cell biological, and histological approaches. |
Tao, Yuan-Xiang |
Molecular and cellular mechanisms that underlie chronic pain and opioid-induced analgesic tolerance and hyperalgesia. |
Thomas, Andrew |
Endocrine regulation of metabolism; calcium signal transduction in liver, heart & brain; mitochondria and cell injury; signaling in malaria; live cell imaging |
Tyagi, Sanjay |
Intracellular dynamics of mRNA synthesis and localization. |
Vatner, Dorothy |
Cellular and molecular signal transduction mechanisms in the cardiovascular system |
Whitehead, Ian |
New treatment modalities for CML. This is a hematopoietic stem cell disorder that accounts for about 25% of all leukemias. |
Wood, Teresa |
Signaling pathways regulating neural and mammary epithelial stem/progenitor cells in normal development, diseases and injury. |
Xie, Lai-hua |
Electrophysiology and Calcium handling in the heart; Cardiac remodeling and mechanisms of arrhythmias in experimental and natural animal models. |
Xu, Ying |
Molecular mechanisms by which epigenetics, environmental and lifestyle factors affect risk of developing Alzheimer’s disease (AD) and neuropsychiatric disorders. Specific research interests include the role of epigenetic modification and mitochondrial phosphodiesterases (PDEs) in AD and dementias. |
Yang, Jason |
Systems and syntheteic biology of chronic and infectious disease. Computational modeling, machine learning, quantitative microscopy, genetic engineering. |
Zarbin, Marco |
Developing cell-based therapy for degenerative retinal disease, including age-related macular degeneration, the leading cause of blindness |
Zhai, Peiyong |
Signaling mechanisms of cardiac myocyte growth and death; and establishing and characterizing animal models of cardiovascular diseases. |