Multidisciplinary PhD Program in
Biomedical Sciences
Infection, Immunity and Inflammation (I3) Track
Faculty Listing |
|
Alland, David |
We have been working to develop a "molecular blood culture" to rapidly identify all common medical pathogens from blood samples, without the need for conventional culture methods. |
Beaulieu, Aimee |
NK cell development and function in viral infection. |
Bell, Samantha |
Innate immune detection and control of Mycobacterium tuberculosis; cell biology and bacterial genetics of macrophage-Mtb interactions |
Bellofatto, Vivian |
Analysis of gene expression in eukaryotic organisms that include pathogens. |
Benevenia, Joseph |
Our department provides exposure to a myriad of musculoskeletal investigations including molecular signaling, tissue engineering, and enhancement of bone healing. |
| Bergsbaken, Tessa Assistant Professor tb553@njms.rutgers.edu |
Tissue-resident memory lymphocyte differentiation and function during infection and malignancy. |
| Bessman, Nicholas Assistant Professor & Chancellor Scholar nb757@connect.rutgers.edu |
Molecular interactions between the microbiota and the immune system, particularly in the context of inflammatory diseases like IBD and cancer. |
Bhanot, Purnima |
We study the molecular mechanisms in the malaria parasite, Plasmodium and its mammalian host that regulate the parasite's development in the host liver. |
Birge, Raymond |
We are interested in the signaling pathways by which normal cells become malignant through the activation of oncogenes. |
Chan, John |
Mycobacterium tuberculosis infection: immunity, immune evasion, latency and reactivation. |
| Chang, Li Yun Associate Professor changth@njms.rutgers.edu |
The role of innate immunity in HIV transmission in the setting of sexually transmitted infection; HIV-human peritoneal macrophage interaction. |
Christakos, Sylvia |
The object of research in the Christakos lab is to obtain a better understanding of the molecular mechanism of action of vitamin D. |
Cugini, Carla |
Molecular mechanisms that govern the in vivo inter- and intra-species interactions within the oral cavity and impact on the host response. |
Dartois, Veronique |
Research activities focus on the pharmacokinetics, efficacy, tissue distribution and imaging of TB drugs, in animal models and in new in vitro assays. |
Diehl, Scott |
We study millions of genetic polymorphisms from arrays or next generation sequencing to reveal the causes of individual differences in disease risk and response |
Douglas, Nataki |
|
Dubnau, David |
We work on the control of developmental processes in bacteria, including competence, sporulation and biofilm formation and on DNA transport for transformation. |
Edelblum, Karen |
Immune/epithelial interactions in gastrointestinal infection and inflammation. |
Elkabes, Stella |
The molecular and cellular mechanisms of neuronal degeneration and protection in animal models of multiple sclerosis and spinal cord injury are investigated. |
Falvo, Michael |
Human cardiopulmonary and bioenergetic responses to environmental stressors |
Fitzgerald-Bocarsly, Patricia |
Our lab focuses on innate immune responses to human viral pathogens. Current work is centered on the basic and clinical biology of plasmacytoid dendritic cells, |
Fraidenraich, Diego |
We study pluripotent stem cell based repair of cardiac and skeletal muscle defects using mouse models of human disease. |
Freundlich, Joel |
We study with chemical tools how pathogens, such as M. tuberculosis, adapt to life within the host and, in turn, how the host responds to the infection. |
Gause, William |
Macrophage function during the type 2 immune response and its role in controlling inflammation and mediating resistance. |
Gennaro, Maria |
(1) Remodeling of M. tuberculosis transcriptome during infection. (2) Mutual signaling between macrophage and pathogen. (3) Immune biomarkers of tuberculosis. |
Goldman, Emanuel |
With PI Wlodek Mandecki , our research has shifted to using genetically engineered EF-Tu to identify a new sub-class of antibiotics. |
Hou, Pingping |
Understand the resistance mechanisms of anti-KRAS therapy and develop cell therapy in pancreatic cancer. |
Humayun, M. Zafri |
Fidelity of DNA replication |
Kaback, David |
The Kaback Lab investigates chromosome structure and function using Saccharomyces cerevisiae. We are most interested in how chromosomes function during meiosis |
Kachlany, Scott |
Our research focuses on the use of a bacterial protein for the treatment of white blood cell diseases. |
Kadouri, Daniel |
Interaction of biofilms and predatory prokaryotes. |
Kim, Hee-Sook |
My lab studies how Trypanosoma brucei, the causative parasite of African sleeping sickness, escapes the host immune response by switching its surface coat protein." |
Kotenko, Sergei |
Research is focused on cytokine-mediated regulation of the immune response to infections and pathologies such as cancer, autoimmune and inflammatory diseases |
Kotsakis , Georgios |
The Translational Periodontal Research Lab focuses on human-centered oral mucosal immunity research using traditional and cutting edge multi-omics modes of investigation to identify how host-microbiome interactions affect healthy tissue homeostasis. |
Kramer, Fred |
Our laboratory has designed novel nucleic acid molecules and developed experimental techniques for extremely sensitive and specific molecular diagnostic assays. |
Kumamoto, Yosuke |
We study the role of dendritic cells and macrophages in inflammation and immunity. |
Levison, Steven |
Effects of maternal inflammation on the resident neural stem cells and progenitors of the developing brain. |
Liu, Dongfang |
Immunobiology of NK and CTLs, with a focus on chimeric antigen receptor (CAR) cells, CAR immunotherapy, and HIV-specific CTLs in chronic HIV and its related malignancies |
Lukac, David |
Regulation of reactivation of oncogenic herpesviruses. Signal transduction and transcriptional responses. Host-virus interactions. |
Lunsford, Keri E. |
We are evaluating the cellular basis for immune dysfunction in cirrhotic patients and how if affects mortality and the development of infections following liver transplant. |
Lutz, Carol |
We are interested in how eukaryotic gene expression regulation (e.g.COX-2) can be accomplished by RNA processing, alt polyadenylation, miRNAs & stability |
Mathews, Michael |
Regulation of gene expression - transcription and translation; viruses (especially HIV) and cancer; drug therapy; molecular and bioinformatic approaches. |
Neiditch, Matthew |
X-ray crystallographic, biochemical, and genetic studies of bacterial signaling. Rational design of antimicrobial compounds. |
O'Connor, James |
We study how inflammation and the innate immune response regulate tissue regeneration with a particular emphasis on lipid mediators and bone regeneration. |
Parker, Dane |
We study host-pathogen interactions between Staphylococcus aureus and Acinetobacter baumannii and the host innate immune pathways that they activate. |
Parveen, Nikhat |
To understand the molecular basis of pathogenesis of Pseudomonas aeruginosa, Lyme disease causing Borrelia burgdorferi and syphilis causing Treponema pallidum. |
Petrou, Vasileios |
Structural studies of membrane enzymes and receptors relevant to antibiotic resistance or human physiology and pathology using single-particle cryo-electron microscopy. |
Pinter, Abraham |
Understanding the basis for the inability of the immune system to control HIV and identifying new targets and approaches to an effective vaccine. |
Rajsbaum, Ricardo |
Host-virus interactions and innate immunity. We focus on the regulation of innate immune pathways and virus replication by ubiquitination, with special interest on Influenza, SARS-CoV-2, Zika and Ebola |
Ramasubbu, Narayanan |
Structural biology of proteins involved in oral diseases and biofilm degradation |
Rivera-Medina, Amariliz |
Our research interest is centered in understanding the development of CD4 T cell responses to the opportunistic fungal pathogen Aspergillus fumigatus. |
Rodriguez, Gloria |
M. tuberculosis (Mtb) iron acquisition, adaptive response of Mtb to iron-deficiency, development of anti-Mtb therapies. |
Rohowsky-Kochan, Christine |
Cytokines; IL-17/IL-23 axis: T regulatory cells; neuroscience; neuroimmunology; multiple sclerosis; autism |
Routh, Vanessa |
Mechanisms by which the brain senses and responds to peripheral nutrient homeostasis and associated dysfunction during obesity, diabetes and disease anorexia |
Salgame, Padmini |
Unraveling immune protective mechanisms against Tuberculosis is axial to the research projects of the Salgame laboratory. |
Shi, Lanbo |
Immunometabolism and host-directed therapy in tuberculosis |
Shimizu, Emi |
Effect of diabetes on dental stem cell machinery to heal tooth injury. Tooth regeneration using iPS cells or oral mucosa stem cells. |
Siracusa, Mark |
My lab investigates the early cellular and molecular events that promote inflammation in the context of protective immunity to helminths and allergic disease. |
Spolarics, Zoltan |
We study the effect of genetic variability on the inflammatory response focusing on X-linked genes and the role of cellular X chromosome mosaicism. |
Stephens, Robin |
Adaptive Immunity and Immunopathology. Immunology: T cell activation, function: cytokines and B cell help, and memory differentiation. Cytokine-induced pathology of Brain: neuro-glial-vascular unit in cerebral malaria, and Lungs: immunoregulation in COVID-19. |
Studzinski, George |
Cancer therapy translational studies of signaling networks that integrate control of cell cycle, apoptosis and vitamin D-induced leukemia cell differentiation. |
Subbian, Selvakumar |
Dr. Subbian’s lab investigates the host immune responses in tuberculosis using mouse, guinea pig and rabbit models as well as in vitro systems. |
Sugimoto, Katsunori |
Our laboratory studies cellular DNA damage response, telomere maintenance, cell senescence and transcriptional control. |
Thomas, Andrew |
Endocrine regulation of metabolism; calcium signal transduction in liver, heart & brain; mitochondria and cell injury; signaling in malaria; live cell imaging |
Tsiagbe, Vincent |
Endogenous retrovirus superantigen in B cell lymphoma; Human endogenous retroviruses in human cancer; Immunologic basis of periodontal disease & bone resorption |
Weinstein, Jason |
Examination of how different T cells and B cells are regulated in autoimmunity compared to infections; understanding the factor(s) that promote and maintain pathogenic T and B cells in autoimmunity. |
Wiesner, Darin |
The Wiesner lab investigates how stromal tissues in the lung provide "context" to inflammation, thereby shaping and sustaining CD4+ T cell responses to fungal allergens and pathogens. |
Wong, Lok-Yin Roy |
Coronavirus biology, immunology and pathogenesis. |
Wong, Tania |
Immunometabolism during bacterial infection |
Xie, Yingda |
We develop and evaluate molecular technologies and radiologic imaging-based tools for active case finding, diagnosis, and personalized treatment of tuberculosis. |
Xue, Chaoyang |
Our research aims to understand the mechanism of fungal infections by using Cryptococcus neoformans as a model organism. The goal is to develop better approache |
Yang, Jason |
Molecular mechanisms underlying pathogenesis and treatment efficacy for chronic and infectious diseases (e.g., tuberculosis, heart failure) using systems biology approaches |
Yap, George |
Regulation of Effector and Memory T cell differentiation by Cytokines, Regulation of the Immune Response by IL-10, Autophagy and Innate Immunity to Toxoplasma gondii. |
Zhao, Xilin |
Bacterial stress response network, a novel, gas-based therapy for tuberculosis, antimicrobial resistance in general, and quinolone mechanisms of action and resistance |
Zhu, Hua |
Our laboratory studies two herpesviruses, human cytomegalovirus (HCMV) and Varicella-Zoster virus (VZV). Our goal is to understand HCMV and VZV pathogenesis. |