Multidisciplinary PhD Program in
Biomedical Sciences
Infection, Immunity and Inflammation (I3) Track
Faculty Listing |
|
Alland, David |
We have been working to develop a "molecular blood culture" to rapidly identify all common medical pathogens from blood samples, without the need for conventional culture methods. |
Beaulieu, Aimee |
NK cell development and function in viral infection. |
Bell, Samantha |
Innate immune detection and control of Mycobacterium tuberculosis; cell biology and bacterial genetics of macrophage-Mtb interactions |
Benevenia, Joseph |
Our department provides exposure to a myriad of musculoskeletal investigations including molecular signaling, tissue engineering, and enhancement of bone healing. |
| Bergsbaken, Tessa Assistant Professor tb553@njms.rutgers.edu |
Tissue-resident memory lymphocyte differentiation and function during infection and malignancy. |
| Bessman, Nicholas Assistant Professor & Chancellor Scholar nb757@connect.rutgers.edu |
Molecular interactions between the microbiota and the immune system, particularly in the context of inflammatory diseases like IBD and cancer. |
Bhanot, Purnima |
We study the molecular mechanisms in the malaria parasite, Plasmodium and its mammalian host that regulate the parasite's development in the host liver. |
Birge, Raymond |
We are interested in the signaling pathways by which normal cells become malignant through the activation of oncogenes. |
Chan, John |
Mycobacterium tuberculosis infection: immunity, immune evasion, latency and reactivation. |
| Chang, Li Yun Associate Professor changth@njms.rutgers.edu |
The role of innate immunity in HIV transmission in the setting of sexually transmitted infection; HIV-human peritoneal macrophage interaction. |
Christakos, Sylvia |
The object of research in the Christakos lab is to obtain a better understanding of the molecular mechanism of action of vitamin D. |
Cugini, Carla |
Molecular mechanisms that govern the in vivo inter- and intra-species interactions within the oral cavity and impact on the host response. |
Diehl, Scott |
We study millions of genetic polymorphisms from arrays or next generation sequencing to reveal the causes of individual differences in disease risk and response |
Douglas, Nataki |
|
Dubnau, David |
We work on the control of developmental processes in bacteria, including competence, sporulation and biofilm formation and on DNA transport for transformation. |
Elkabes, Stella |
The molecular and cellular mechanisms of neuronal degeneration and protection in animal models of multiple sclerosis and spinal cord injury are investigated. |
Falvo, Michael |
Human cardiopulmonary and bioenergetic responses to environmental stressors |
Fitzgerald-Bocarsly, Patricia |
Our lab focuses on innate immune responses to human viral pathogens. Current work is centered on the basic and clinical biology of plasmacytoid dendritic cells, |
Fraidenraich, Diego |
We study pluripotent stem cell based repair of cardiac and skeletal muscle defects using mouse models of human disease. |
Freundlich, Joel |
We study with chemical tools how pathogens, such as M. tuberculosis, adapt to life within the host and, in turn, how the host responds to the infection. |
Gause, William |
Macrophage function during the type 2 immune response and its role in controlling inflammation and mediating resistance. |
Gennaro, Maria |
(1) Remodeling of M. tuberculosis transcriptome during infection. (2) Mutual signaling between macrophage and pathogen. (3) Immune biomarkers of tuberculosis. |
Goldman, Emanuel |
With PI Wlodek Mandecki , our research has shifted to using genetically engineered EF-Tu to identify a new sub-class of antibiotics. |
| Hargarten, Jessica Assistant Professor jessica.hargarten@rutgers.edu |
The Hargarten Lab's overarching goal is to define and interrogate the major human genetic, immunologic, and lifestyle factors that contribute to susceptibility to severe fungal disease. |
Hou, Pingping |
Understand the resistance mechanisms of anti-KRAS therapy and develop cell therapy in pancreatic cancer. |
Hsu, Chun-Chieh (Jack) |
We study the molecular arms race between the immune system and viruses, particularly interested in the interferon response, SARS-CoV-2, flavivirus and influenza virus. Lab website: https://jackhsu.org/ |
Kaback, David |
The Kaback Lab investigates chromosome structure and function using Saccharomyces cerevisiae. We are most interested in how chromosomes function during meiosis |
Kachlany, Scott |
Our research focuses on the use of a bacterial protein for the treatment of white blood cell diseases. |
Kadouri, Daniel |
Interaction of biofilms and predatory prokaryotes. |
Kim, Hee-Sook |
My lab studies how Trypanosoma brucei, the causative parasite of African sleeping sickness, escapes the host immune response by switching its surface coat protein." |
Kotenko, Sergei |
Research is focused on cytokine-mediated regulation of the immune response to infections and pathologies such as cancer, autoimmune and inflammatory diseases |
Kotsakis , Georgios |
The Translational Periodontal Research Lab focuses on human-centered oral mucosal immunity research using traditional and cutting edge multi-omics modes of investigation to identify how host-microbiome interactions affect healthy tissue homeostasis. |
Kramer, Fred |
Our laboratory has designed novel nucleic acid molecules and developed experimental techniques for extremely sensitive and specific molecular diagnostic assays. |
Kumamoto, Yosuke |
We study the role of dendritic cells and macrophages in inflammation and immunity. |
Kumar, Pradeep |
Tuberculosis and NTM: discovering new drugs, novel targets, understanding resistance and tolerance. |
Levison, Steven |
Effects of maternal inflammation on the resident neural stem cells and progenitors of the developing brain. |
Liu, Dongfang |
Immunobiology of NK and CTLs, with a focus on chimeric antigen receptor (CAR) cells, CAR immunotherapy, and HIV-specific CTLs in chronic HIV and its related malignancies |
Lukac, David |
Regulation of reactivation of oncogenic herpesviruses. Signal transduction and transcriptional responses. Host-virus interactions. |
Lunsford, Keri E. |
We are evaluating the cellular basis for immune dysfunction in cirrhotic patients and how if affects mortality and the development of infections following liver transplant. |
Lutz, Carol |
We are interested in how eukaryotic gene expression regulation (e.g.COX-2) can be accomplished by RNA processing, alt polyadenylation, miRNAs & stability |
Mathews, Michael |
Regulation of gene expression - transcription and translation; viruses (especially HIV) and cancer; drug therapy; molecular and bioinformatic approaches. |
Miskolci, Veronika |
We are broadly interested in how the innate immune response is regulated during inflammation and sterile injuries. |
Neiditch, Matthew |
X-ray crystallographic, biochemical, and genetic studies of bacterial signaling. Rational design of antimicrobial compounds. |
O'Connor, James |
We study how inflammation and the innate immune response regulate tissue regeneration with a particular emphasis on lipid mediators and bone regeneration. |
Parker, Dane |
We study host-pathogen interactions between Staphylococcus aureus and Acinetobacter baumannii and the host innate immune pathways that they activate. |
Parveen, Nikhat |
To understand the molecular basis of pathogenesis of Pseudomonas aeruginosa, Lyme disease causing Borrelia burgdorferi and syphilis causing Treponema pallidum. |
Petrou, Vasileios |
Structural studies of membrane enzymes and receptors relevant to antibiotic resistance or human physiology and pathology using single-particle cryo-electron microscopy. |
Pinter, Abraham |
Understanding the basis for the inability of the immune system to control HIV and identifying new targets and approaches to an effective vaccine. |
Rajsbaum, Ricardo |
Host-virus interactions and innate immunity. We focus on the regulation of innate immune pathways and virus replication by ubiquitination, with special interest on Influenza, SARS-CoV-2, Zika and Ebola |
Ramasubbu, Narayanan |
Structural biology of proteins involved in oral diseases and biofilm degradation |
Rivera-Medina, Amariliz |
Our research interest is centered in understanding the development of CD4 T cell responses to the opportunistic fungal pathogen Aspergillus fumigatus. |
Rodriguez, Gloria |
M. tuberculosis (Mtb) iron acquisition, adaptive response of Mtb to iron-deficiency, development of anti-Mtb therapies. |
Rohowsky-Kochan, Christine |
Cytokines; IL-17/IL-23 axis: T regulatory cells; neuroscience; neuroimmunology; multiple sclerosis; autism |
Routh, Vanessa |
Mechanisms by which the brain senses and responds to peripheral nutrient homeostasis and associated dysfunction during obesity, diabetes and disease anorexia |
Salgame, Padmini |
Unraveling immune protective mechanisms against Tuberculosis is axial to the research projects of the Salgame laboratory. |
Shi, Lanbo |
Immunometabolism and host-directed therapy in tuberculosis |
Shimizu, Emi |
Effect of diabetes on dental stem cell machinery to heal tooth injury. Tooth regeneration using iPS cells or oral mucosa stem cells. |
Siracusa, Mark |
My lab investigates the early cellular and molecular events that promote inflammation in the context of protective immunity to helminths and allergic disease. |
Stephens, Robin |
Adaptive Immunity and Immunopathology. Immunology: T cell activation, function: cytokines and B cell help, and memory differentiation. Cytokine-induced pathology of Brain: neuro-glial-vascular unit in cerebral malaria, and Lungs: immunoregulation in COVID-19. |
Subbian, Selvakumar |
Dr. Subbian’s lab investigates the host immune responses in tuberculosis using mouse, guinea pig and rabbit models as well as in vitro systems. |
Sugimoto, Katsunori |
Our laboratory studies cellular DNA damage response, telomere maintenance, cell senescence and transcriptional control. |
Thomas, Andrew |
Endocrine regulation of metabolism; calcium signal transduction in liver, heart & brain; mitochondria and cell injury; signaling in malaria; live cell imaging |
Tsiagbe, Vincent |
Endogenous retrovirus superantigen in B cell lymphoma; Human endogenous retroviruses in human cancer; Immunologic basis of periodontal disease & bone resorption |
Weinstein, Jason |
Examination of how different T cells and B cells are regulated in autoimmunity compared to infections; understanding the factor(s) that promote and maintain pathogenic T and B cells in autoimmunity. |
Wiesner, Darin |
The Wiesner lab investigates how stromal tissues in the lung provide "context" to inflammation, thereby shaping and sustaining CD4+ T cell responses to fungal allergens and pathogens. |
Wong, Lok-Yin Roy |
Coronavirus biology, immunology and pathogenesis. |
Wong, Tania |
Immunometabolism during bacterial infection |
Xie, Yingda |
We develop and evaluate molecular technologies and radiologic imaging-based tools for active case finding, diagnosis, and personalized treatment of tuberculosis. |
Xue, Chaoyang |
Our research aims to understand the mechanism of fungal infections by using Cryptococcus neoformans as a model organism. The goal is to develop better approache |
Yang, Jason |
Molecular mechanisms underlying pathogenesis and treatment efficacy for chronic and infectious diseases (e.g., tuberculosis, heart failure) using systems biology approaches |
Yap, George |
Regulation of Effector and Memory T cell differentiation by Cytokines, Regulation of the Immune Response by IL-10, Autophagy and Innate Immunity to Toxoplasma gondii. |
Zhang, Wen |
How the peripheral nervous system senses and regulates immunity at mucosal barrier tissues. Our lab investigates how sensory neurons interact with the microbiota, intestinal epithelial cells, and immune cells to control immune tolerance, inflammation, and tissue protection. |