Multidisciplinary PhD Program in
Biomedical Sciences
Molecular Biology, Genetics and Cancer (MBGC) Track
Faculty Listing |
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Astrof, Sophie |
Molecular mechanisms and signaling pathways in cardiovascular development and remodeling. |
Bell, Samantha
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Innate immune detection and control of Mycobacterium tuberculosis; cell biology and bacterial genetics of macrophage-Mtb interactions |
Bellofatto, Vivian |
Analysis of gene expression in eukaryotic organisms that include pathogens. |
Benevenia, Joseph |
Our department provides exposure to a myriad of musculoskeletal investigations including molecular signaling, tissue engineering, enhancement of bone healing, m |
Berlin, Joshua |
P-type active ion transporters: ion transport mechanism and roles in disease processes. Cellular mechanisms underlying acute traumatic brain injury. |
Bhanot, Purnima |
We study the molecular mechanisms in the malaria parasite, Plasmodium and its mammalian host that regulate the parasite's development in the host liver. |
Birge, Raymond |
We are interested in the signaling pathways by which normal cells become malignant through the activation of oncogenes. |
Christakos, Sylvia |
The object of research in the Christakos lab is to obtain a better understanding of the molecular mechanism of action of vitamin D |
Diehl, Scott |
We study millions of genetic polymorphisms from arrays or next generation sequencing to reveal the causes of individual differences in disease risk and response |
Douglas, Nataki |
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Dubnau, David |
We work on the control of developmental processes in bacteria, including competence, sporulation and biofilm formation and on DNA transport for transformation. |
Fitzgerald-Bocarsly, Patricia |
Our lab focuses on innate immune responses to human viral pathogens. Current work is centered on the basic and clinical biology of plasmacytoid dendritic cells, |
Fraidenraich, Diego |
We study pluripotent stem cell based repair of cardiac and skeletal muscle defects using mouse models of human disease. |
Freundlich, Joel |
We study with chemical tools how pathogens, such as M. tuberculosis, adapt to life within the host and, in turn, how the host responds to the infection. |
Gennaro, Maria |
(1) Remodeling of M. tuberculosis transcriptome during infection. (2) Mutual signaling between macrophage and pathogen. (3) Immune biomarkers of tuberculosis. |
Goldman, Emanuel |
With PI Wlodek Mandecki , our research has shifted to using genetically engineered EF-Tu to identify a new sub-class of antibiotics. |
Herbig, Utz |
My laboratory studies telomere dysfunction, cellular senescence, and the role of cellular senescence in cancer and aging. |
Hilfiker, Sabine |
Molecular mechanisms underlying Parkinson“s disease, determination of pathological cell biologial events and signaling cascades to uncover disease-modifying targets and strategies. |
Hou, Pingping |
Understand the resistance mechanisms of anti-KRAS therapy and develop cell therapy in pancreatic cancer. |
Kaback, David |
The Kaback Lab investigates chromosome structure and function using Saccharomyces cerevisiae. We are most interested in how chromosomes function during meiosis |
Kim, Hee-Sook
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My lab studies how Trypanosoma brucei, the causative parasite of African sleeping sickness, escapes the host immune response by switching its surface coat protein." |
Kotenko, Sergei |
Research is focused on cytokine-mediated regulation of the immune response to infections and pathologies such as cancer, autoimmune and inflammatory diseases |
Kramer, Fred |
Our laboratory has designed novel nucleic acid molecules and developed experimental techniques for extremely sensitive and specific molecular diagnostic assays. |
Lambert, Muriel |
Genomic instability and cancer predisposition diseases; the hematological disorder, Fanconi anemia, and the role defective DNA repair plays in this disorder |
Lear, Travis Assistant Professor travis.lear@rutgers.edu |
Regulation and biologic consequence of cellular proteostasis, with a focus on the intersection of the ubiquitin proteasome system and lysosomal biology, and how these systems affect aging, cellular metabolism, and neurodegenerative disease. Central in this question is identifying key proteins regulating auto-lysosomal biology, mapping the mechanisms controlling their protein stability, and seeking to intervene in their degradation |
Liu, Dongfang |
Immunobiology of NK and CTLs, with a focus on chimeric antigen receptor (CAR) cells, CAR immunotherapy, and HIV-specific CTLs in chronic HIV and its related malignancies |
Li, Hong |
My lab aims to develop mass spectrometry technologies to study the role of protein post-translational modifications and protein-protein interactions in regulation. |
Lukac, David |
Regulation of reactivation of oncogenic herpesviruses. Signal transduction and transcriptional responses. Host-virus interactions. |
Lutz, Carol |
We are interested in how eukaryotic gene expression regulation (e.g.COX-2) can be accomplished by RNA processing, alt polyadenylation, miRNAs & stability |
Mathews, Michael |
Regulation of gene expression - transcription and translation; viruses (especially HIV) and cancer; drug therapy; molecular and bioinformatic approaches. |
Miskolci, Veronika |
We are broadly interested in how the innate immune response is regulated during inflammation and sterile injuries. |
Mitrofanova, Antonina |
My laboratory develops computational algorithms to elucidate genomic, transcriptomic, and epigenomic mechanisms of therapeutic resistance in oncology and to identify optimal treatment strategies for cancer patients. Our goal is to build a panel of markers to predict patients at risk of treatment resistance, with further advice on their optimal therapeutic course. |
Neiditch, Matthew |
X-ray crystallographic, biochemical, and genetic studies of bacterial signaling. Rational design of antimicrobial compounds. |
O'Connor, James |
We study how inflammation and the innate immune response regulate tissue regeneration with a particular emphasis on lipid mediators and bone regeneration. |
Olarerin-George, Anthony |
Discovering the function and regulation of RNA chemical modifications in the cell using biochemical, molecular and computational biology approaches. |
Papachristodoulou, Alex |
molecular and cellular mechanisms of prostate carcinogenesis |
Park, Yongkyu |
Regulation of longevity by Imd and Loco signaling pathways in fruitflies |
Parveen, Nikhat |
To understand the molecular basis of pathogenesis of Pseudomonas aeruginosa, Lyme disease causing Borrelia burgdorferi and syphilis causing Treponema pallidum. |
Perlin, David |
The Perlin lab is interested in mechanisms of antifungal drug resistance, rapid detection of drug resistant bloodstream and respiratory pathogens in high-risk p |
Petrou, Vasileios |
Structural studies of membrane enzymes and receptors relevant to antibiotic resistance or human physiology and pathology using single-particle cryo-electron microscopy. |
Rogers, Melissa |
Studies of transcriptional & post-transcriptional Bone Morphogenetic Protein 2 gene regulation as relevant to embryogenesis, cancer, & vascular calcification. |
Rohacs, Tibor |
Structure and function studies on Transient Receptor Potential (TRP) and mechanically activated Piezo ion channels. |
Routh, Vanessa |
Mechanisms by which the brain senses and responds to peripheral nutrient homeostasis and associated dysfunction during obesity, diabetes and disease anorexia |
Suzuki, Carolyn |
Mitochondrial biogenesis and apoptosis Mitochondrial ATP-dependent proteases & chaperones Inhibitors to these proteases & chaperones to treat human disease |
Tsiagbe, Vincent |
Endogenous retrovirus superantigen in B cell lymphoma; Human endogenous retroviruses in human cancer; Immunologic basis of periodontal disease & bone resorption |
Tyagi, Sanjay |
We study the intracellular dynamics of mRNA synthesis and localization. |
Whitehead, Ian |
My laboratory is investigating new treatment modalities for CML. This is a hematopoietic stem cell disorder that accounts for about 25% of all leukemias. |
Wieder, Robert |
Our laboratory studies the mechanisms of dormancy and resistance to chemotherapy in breast cancer cells that metastasize to the bone marrow. |
Wood, Teresa |
Signaling pathways regulating neural and mammary epithelial stem/progenitor cells in normal development, diseases and injury. |
Yadav, Vijay |
evolutionarily conserved mechanisms of aging, how nutrients such as vitamin B12 and taurine regulate aging |
Yang, Jason |
Molecular mechanisms underlying pathogenesis and treatment efficacy for chronic and infectious diseases (e.g., tuberculosis, heart failure) using systems biology approaches |
Zhao, Xilin |
Bacterial stress response network, a novel, gas-based therapy for tuberculosis, antimicrobial resistance in general, and quinolone mechanisms of action and resi |