Multidisciplinary PhD Program in
Biomedical Sciences
Molecular Biology, Genetics and Cancer (MBGC) Track
Faculty Listing |
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Astrof, Sophie |
Molecular mechanisms and signaling pathways in cardiovascular development and remodeling. |
Bell, Samantha
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Innate immune detection and control of Mycobacterium tuberculosis; cell biology and bacterial genetics of macrophage-Mtb interactions |
Bellofatto, Vivian |
Analysis of gene expression in eukaryotic organisms that include pathogens. |
Benevenia, Joseph |
Our department provides exposure to a myriad of musculoskeletal investigations including molecular signaling, tissue engineering, enhancement of bone healing, m |
Berlin, Joshua |
P-type active ion transporters: ion transport mechanism and roles in disease processes. Cellular mechanisms underlying acute traumatic brain injury. |
Bhanot, Purnima |
We study the molecular mechanisms in the malaria parasite, Plasmodium and its mammalian host that regulate the parasite's development in the host liver. |
Birge, Raymond |
We are interested in the signaling pathways by which normal cells become malignant through the activation of oncogenes. |
Christakos, Sylvia |
The object of research in the Christakos lab is to obtain a better understanding of the molecular mechanism of action of vitamin D |
Diehl, Scott |
We study millions of genetic polymorphisms from arrays or next generation sequencing to reveal the causes of individual differences in disease risk and response |
Douglas, Nataki |
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Dubnau, David |
We work on the control of developmental processes in bacteria, including competence, sporulation and biofilm formation and on DNA transport for transformation. |
Fitzgerald-Bocarsly, Patricia |
Our lab focuses on innate immune responses to human viral pathogens. Current work is centered on the basic and clinical biology of plasmacytoid dendritic cells, |
Fraidenraich, Diego |
We study pluripotent stem cell based repair of cardiac and skeletal muscle defects using mouse models of human disease. |
Freundlich, Joel |
We study with chemical tools how pathogens, such as M. tuberculosis, adapt to life within the host and, in turn, how the host responds to the infection. |
Gennaro, Maria |
(1) Remodeling of M. tuberculosis transcriptome during infection. (2) Mutual signaling between macrophage and pathogen. (3) Immune biomarkers of tuberculosis. |
Goldman, Emanuel |
With PI Wlodek Mandecki , our research has shifted to using genetically engineered EF-Tu to identify a new sub-class of antibiotics. |
Herbig, Utz |
My laboratory studies telomere dysfunction, cellular senescence, and the role of cellular senescence in cancer and aging. |
Hilfiker, Sabine |
Molecular mechanisms underlying Parkinson´s disease, determination of pathological cell biologial events and signaling cascades to uncover disease-modifying targets and strategies. |
Hou, Pingping |
Understand the resistance mechanisms of anti-KRAS therapy and develop cell therapy in pancreatic cancer. |
Kaback, David |
The Kaback Lab investigates chromosome structure and function using Saccharomyces cerevisiae. We are most interested in how chromosomes function during meiosis |
Kim, Hee-Sook
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My lab studies how Trypanosoma brucei, the causative parasite of African sleeping sickness, escapes the host immune response by switching its surface coat protein." |
Kotenko, Sergei |
Research is focused on cytokine-mediated regulation of the immune response to infections and pathologies such as cancer, autoimmune and inflammatory diseases |
Kramer, Fred |
Our laboratory has designed novel nucleic acid molecules and developed experimental techniques for extremely sensitive and specific molecular diagnostic assays. |
Lambert, Muriel |
Genomic instability and cancer predisposition diseases; the hematological disorder, Fanconi anemia, and the role defective DNA repair plays in this disorder |
Liu, Dongfang |
Immunobiology of NK and CTLs, with a focus on chimeric antigen receptor (CAR) cells, CAR immunotherapy, and HIV-specific CTLs in chronic HIV and its related malignancies |
Li, Hong |
My lab aims to develop mass spectrometry technologies to study the role of protein post-translational modifications and protein-protein interactions in regulation. |
Lukac, David |
Regulation of reactivation of oncogenic herpesviruses. Signal transduction and transcriptional responses. Host-virus interactions. |
Lutz, Carol |
We are interested in how eukaryotic gene expression regulation (e.g.COX-2) can be accomplished by RNA processing, alt polyadenylation, miRNAs & stability |
Mathews, Michael |
Regulation of gene expression - transcription and translation; viruses (especially HIV) and cancer; drug therapy; molecular and bioinformatic approaches. |
Mitrofanova, Antonina |
My laboratory develops computational algorithms to elucidate genomic, transcriptomic, and epigenomic mechanisms of therapeutic resistance in oncology and to identify optimal treatment strategies for cancer patients. Our goal is to build a panel of markers to predict patients at risk of treatment resistance, with further advice on their optimal therapeutic course. |
Neiditch, Matthew |
X-ray crystallographic, biochemical, and genetic studies of bacterial signaling. Rational design of antimicrobial compounds. |
O'Connor, James |
We study how inflammation and the innate immune response regulate tissue regeneration with a particular emphasis on lipid mediators and bone regeneration. |
Olarerin-George, Anthony |
Discovering the function and regulation of RNA chemical modifications in the cell using biochemical, molecular and computational biology approaches. |
Park, Yongkyu |
Regulation of longevity by Imd and Loco signaling pathways in fruitflies |
Parveen, Nikhat |
To understand the molecular basis of pathogenesis of Pseudomonas aeruginosa, Lyme disease causing Borrelia burgdorferi and syphilis causing Treponema pallidum. |
Perlin, David |
The Perlin lab is interested in mechanisms of antifungal drug resistance, rapid detection of drug resistant bloodstream and respiratory pathogens in high-risk p |
Petrou, Vasileios |
Structural studies of membrane enzymes and receptors relevant to antibiotic resistance or human physiology and pathology using single-particle cryo-electron microscopy. |
Rogers, Melissa |
Studies of transcriptional & post-transcriptional Bone Morphogenetic Protein 2 gene regulation as relevant to embryogenesis, cancer, & vascular calcification. |
Rohacs, Tibor |
Structure and function studies on Transient Receptor Potential (TRP) and mechanically activated Piezo ion channels. |
Routh, Vanessa |
Mechanisms by which the brain senses and responds to peripheral nutrient homeostasis and associated dysfunction during obesity, diabetes and disease anorexia |
Suzuki, Carolyn |
Mitochondrial biogenesis and apoptosis Mitochondrial ATP-dependent proteases & chaperones Inhibitors to these proteases & chaperones to treat human disease |
Tsiagbe, Vincent |
Endogenous retrovirus superantigen in B cell lymphoma; Human endogenous retroviruses in human cancer; Immunologic basis of periodontal disease & bone resorption |
Tyagi, Sanjay |
We study the intracellular dynamics of mRNA synthesis and localization. |
Whitehead, Ian |
My laboratory is investigating new treatment modalities for CML. This is a hematopoietic stem cell disorder that accounts for about 25% of all leukemias. |
Wieder, Robert |
Our laboratory studies the mechanisms of dormancy and resistance to chemotherapy in breast cancer cells that metastasize to the bone marrow. |
Wood, Teresa |
Signaling pathways regulating neural and mammary epithelial stem/progenitor cells in normal development, diseases and injury. |
Yang, Jason |
Molecular mechanisms underlying pathogenesis and treatment efficacy for chronic and infectious diseases (e.g., tuberculosis, heart failure) using systems biology approaches |
Zhao, Xilin |
Bacterial stress response network, a novel, gas-based therapy for tuberculosis, antimicrobial resistance in general, and quinolone mechanisms of action and resi |