Recent Publications

1. Velloso F.J., Wadhwa A., Kumari E., Carcea I., Gunal O., Levison S.W. (2022) Modestly increasing systemic interleukin-6 perinatally disturbs secondary germinal zone neurogenesis and gliogenesis and produces sociability deficits. Brain Behav Immun. 2022 Mar;101:23-36.

2. Khandker L., Jeffries M.A., Chang Y., Mather M.L., Bourne J.N., Tafreshi A.K., Ornelas I.M, Bozdagi-Gunal O., Macklin W. and Wood T.L. (2021) Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord. Cell Rep. 2022 Mar 1;38(9):110423.

3. Sahasrabudhe A., Begum F., Guevara C.A., Morrison C., Hsiao K., Kezunovic N., Bozdagi-Gunal O., Benson D.L. (2021) Cyfip1 regulates SynGAP1 at Hippocampal Synapses. Frontiers in Synaptic Neuroscience, 05 February

4. Hayretdag C., Algedik P., Ekmekci C.G., Agyuz U., Bozdagi-Gunal O., Coskunpinar E. (2020) Determination of Genetic Changes in Etiology of Autism Spectrum Disorder in Twins by Whole-Exome Array. Gene Report, Volume 19, June 2020, 100618

5. Lachance V., Wang Q., Sweet E., Choi I., Cai C., Zhuang X., Zhang Y., Jiang J., Blitzer R.D., Bozdagi-Gunal O., Zhang B., Lu J., Yue Z. (2019) Autophagy protein NRBF2 has rescued expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice. Mol Neurodegener. 2019 Nov 27;14(1):43. PMID: 31775806

6. Harony-Nicolas H, Kay M, Hoffmann JD, Klein ME, Bozdagi-Gunal O, Riad M, Daskalakis NP, Sonar S, Castillo PE, Hof PR, Shapiro ML, Baxter MG, Wagner S, Buxbaum JD.  Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat. Elife. 2017 Jan 31;6. PMID: 28139198

7. Kajiwara Y., McKenzie A., Dorr N., Gama Sosa M.A., Elder G., Schmeidler J., Dickstein D.L., Bozdagi O., Zhang B., Buxbaum J.D. The human-specific CASP4 gene product contributes to Alzheimer-related synaptic and behavioural deficits. Hum Mol Genet. 2016 Aug 11. pii: ddw265. PMID: 27516385

8. Hsiao K., Nicolas-Harony H., Buxbaum J.D., Bozdagi-Gunal O.*, Benson D.*; Cyfip1 regulates presynaptic function during development via WAVE1. Journal of Neuroscience February 3; 36(5):1564 –1576 (2016).

9. Kajiwara, Y., Schiff, T., Voloudakis, G., Gama-Sosa, M., Elder, G., Bozdagi, O., Buxbaum, J.D. (2014) A critical role for human caspase-4 in endotoxin sensitivity. Journal of Immunology. May 30. PMID: 24879791

10. Hsiao, K., Bozdagi, O. and Benson, D. Cap-dependent translation regulates presynaptic P35. Developmental Neurobiology. Nov 19 (2014) PMID: 24254883

11. Bozdagi, O., Tavassoli, T., Buxbaum, J.D. Insulin-like growth factor-1 rescues synaptic and motor deficits in a mouse model of autism and developmental delay. Molecular Autism. Apr 27;4(1):9 (2013) PMID: 23621888

12. Bozdagi, O., Sakurai, T., Dorr, N., Pilorge, M., Takahashi, N., Buxbaum, J.D. Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice. PLoS One; 7(8): e42422 (2012)

13. Suzuki, A., Stern, S.*, Bozdagi, O.*, Huntley, G. W., Magistretti, P. and Alberini, C. M. The astrocyte-neuronal lactate-shuttle is required for long-term memory formation. Cell. Mar 4;144(5):810-23 (2011) PMID: 21376239

14. Bozdagi, O., Wang, X., Martinelli, G.P., Prell, G.D., Friedrich, V.L. Jr, Huntley, G.W., Holstein, G.R. Imidazoleacetic acid-Ribotide Induces Depression of Synaptic Responses in Hippocampus Through Activation of Imidazoline Receptors. Journal of Neurophysiology, Jan 12 (2011) PMID: 21228308 NIHMSID 270360

15. Bozdagi, O., Sakurai, T., Papapetrou, D., Wang, X., Dickstein, D.L., Takahashi, N., Kajiwara, Y., Yang, M., Katz, A.M., Scattoni, M.L., Harris, M.J., Saxena, R., Silverman, J.L., Crawley, J.N., Zhou, Q., Hof, P.R., Buxbaum, J.D. Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication. Molecular Autism. Dec 17;1(1):15 (2010) PMID: 21167025 PMC3019144

16. Bozdagi, O., Wang, X.B., Nikitczuk, J.S., Anderson, T.R., Bloss, E.B., Radice, G.L., Zhou, Q., Benson, D.L., Huntley, G.W. Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal CA1 synapses requires N-cadherin. Journal of Neuroscience, Jul 28;30 (30):9984-9 (2010) PMID: 20668183 PMC2921177

17. Wang, X.B., Bozdagi, O., Nikitczuk, J.S., Zhai, Z.W., Zhou, Q., Huntley, G.W. Extracellular proteolysis by matrix metalloproteinase-9 drives dendritic spine enlargement and long-term potentiation coordinately. Proceedings of National Academy of Sciences U S A. Dec 9;105 (49):19520-5 (2008) PMID: 19047646PMC2614793

18. Bozdagi, O., Rich, E., Tronel, S., Sadahiro, M., Patterson, K., Shapiro, M.L., Alberini, C.M., Huntley, G.W., Salton, S.R. The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism. Journal of Neuroscience, Sep 24;28 (39):9857-69 (2008) PMID: 18815270 PMC2820295

19. Nagy, V., Bozdagi, O. and Huntley, G. W. The extracellular protease matrix metalloproteinase-9 is activated by inhibitory avoidance learning and required for long-term memory. Learning and Memory 14: 655-664 (2007) PMID: 17909100 PMC 2044557

20. Bozdagi, O., Nagy, V., Kimberly, K. and Huntley, G. W. In vivo roles for matrix metalloproteinase-9 in mature hippocampal synaptic physiology and plasticity. Journal of Neurophysiology, Jul;98 (1):334-44 (2007) PMID: 17493927 NIHMSID 270369

21. Nagy, V.*, Bozdagi, O.*, Matynia, A., Balcerzyk, M., Okulski, P., Dzwonek, J., Costa, R. M., Silva, A. J., Kaczmarek, L., and Huntley, G. W. Matrix Metalloproteinase-9 Is Required for Hippocampal Late-Phase Long-Term Potentiation and Memory. Journal of Neuroscience, 26(7):1923–1934 (2006) PMID: 16481424 NIHMSID 270379

22. Bozdagi, O., Shan,W. S., Tanaka, H., Benson, D.L. and Huntley, G.W. Increasing numbers of synaptic puncta during late-phase LTP: N-cadherin is synthesized, recruited to synaptic sites and required for potentiation. Neuron, 28: 245–259 (2000) PMID: 11086998